Support for linkage to variation in CC-GFR* in different groups of relatives
| Chromosome . | Closest marker† . | Location (cM)‡ . | Max. LOD score§ . | Nominal P . | Empirical P . | LOD-1 interval (Mb) . |
|---|---|---|---|---|---|---|
| Diabetic relative pairs | ||||||
| 2q | D2S1384 | 202 | 4.1 | 6.2 × 10−6 | 2 × 10−5 | 195–213 |
| 10q‖ | D10S2470–D10S677 | 114 | 3.6 | 2.5 × 10−5 | 1.2 × 10−4 | 85–101 |
| 18p | D18S843 | 28 | 2.2 | 7.0 × 10−4 | 2.4 × 10−3 | 6–10 |
| Nondiabetic relative pairs | ||||||
| 3q | D3S1744 | 161 | 2.2 | 6.6 × 10−4 | 1.2 × 10−3 | 138–152 |
| 11p | D11S1993 | 52 | 2.1 | 8.0 × 10−4 | 1.6 × 10−3 | 36–53 |
| All relative pairs | ||||||
| 7p | D7S3047–D7S3051 | 23 | 4.0 | 9.8 × 10−6 | 4 × 10−5 | 6–26 |
| Chromosome . | Closest marker† . | Location (cM)‡ . | Max. LOD score§ . | Nominal P . | Empirical P . | LOD-1 interval (Mb) . |
|---|---|---|---|---|---|---|
| Diabetic relative pairs | ||||||
| 2q | D2S1384 | 202 | 4.1 | 6.2 × 10−6 | 2 × 10−5 | 195–213 |
| 10q‖ | D10S2470–D10S677 | 114 | 3.6 | 2.5 × 10−5 | 1.2 × 10−4 | 85–101 |
| 18p | D18S843 | 28 | 2.2 | 7.0 × 10−4 | 2.4 × 10−3 | 6–10 |
| Nondiabetic relative pairs | ||||||
| 3q | D3S1744 | 161 | 2.2 | 6.6 × 10−4 | 1.2 × 10−3 | 138–152 |
| 11p | D11S1993 | 52 | 2.1 | 8.0 × 10−4 | 1.6 × 10−3 | 36–53 |
| All relative pairs | ||||||
| 7p | D7S3047–D7S3051 | 23 | 4.0 | 9.8 × 10−6 | 4 × 10−5 | 6–26 |
Covariates used for adjustment of CC-GFR (see research design and methods).
Name of one marker is provided if it coincides with the peak of the maximum (Max.) LOD score, names of two markers are provided if the peak of the maximum LOD score is located between markers.
Position according to Marshfield map.
Multipoint LOD score.
Results from the set of Caucasians only.