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TABLE 1

Characteristics of the study subjects

All subjectsNAFL−NAFL+
n 24 16 
Histological liver fat (%) 38.5 ± 6.8 2.6 ± 1.2 56.4 ± 6.5* 
Women/men 14/10 4/4 10/6 
Age (years) 44 ± 2 47 ± 4 42 ± 3 
Body weight (kg) 105 ± 6 85 ± 9 116 ± 8 
BMI (kg/m237.1 ± 2.4 29.9 ± 3.8 40.8 ± 2.6 
Components of the MetS    
    Waist circumference (cm) 113 ± 4 85 ± 9 116 ± 8 
    Systolic blood pressure (mmHg) 133 ± 2 130 ± 5 134 ± 3 
    Diastolic blood pressure (mmHg) 83 ± 2 78 ± 3 86 ± 2 
    fS triglycerides (mmol/l) 1.7 ± 0.2 1.1 ± 0.2 1.9 ± 0.2 
    fS HDL cholesterol (mmol/l) 1.5 ± 0.1 2 ± 0.3 1.3 ± 0.1 
    fP glucose (mmol/l) 5.9 ± 0.2 5.3 ± 0.2 6.1 ± 0.3 
Other parameters    
    fS insulin (mU/l) 12 ± 2 6 ± 1 15 ± 3 
    fS C-peptide (nmol/l) 0.9 ± 0.1 0.6 ± 0.1 1.1 ± 0.1 
    fS FFA (μmol/l) 588 ± 45 509 ± 90 628 ± 49 
    fS adiponectin (μg/ml) 9.7 ± 1 12.3 ± 2.1 8.4 ± 1§ 
    fP PAI-1 (ng/ml) 31 ± 3 24 ± 6 35 ± 3 
    fS LDL cholesterol (mmol/l) 2.7 ± 0.2 2.7 ± 0.3 2.7 ± 0.2 
    fS ALT (units/l) 87 ± 13 97 ± 21 82 ± 17 
    fS AST (units/l) 53 ± 6 55 ± 9 53 ± 8 
    MCV (fl) 90 ± 1 90 ± 1 90 ± 1 
    Daily alcohol dose 0.5 ± 0.2 0.4 ± 0.2 0.5 ± 0.2 
All subjectsNAFL−NAFL+
n 24 16 
Histological liver fat (%) 38.5 ± 6.8 2.6 ± 1.2 56.4 ± 6.5* 
Women/men 14/10 4/4 10/6 
Age (years) 44 ± 2 47 ± 4 42 ± 3 
Body weight (kg) 105 ± 6 85 ± 9 116 ± 8 
BMI (kg/m237.1 ± 2.4 29.9 ± 3.8 40.8 ± 2.6 
Components of the MetS    
    Waist circumference (cm) 113 ± 4 85 ± 9 116 ± 8 
    Systolic blood pressure (mmHg) 133 ± 2 130 ± 5 134 ± 3 
    Diastolic blood pressure (mmHg) 83 ± 2 78 ± 3 86 ± 2 
    fS triglycerides (mmol/l) 1.7 ± 0.2 1.1 ± 0.2 1.9 ± 0.2 
    fS HDL cholesterol (mmol/l) 1.5 ± 0.1 2 ± 0.3 1.3 ± 0.1 
    fP glucose (mmol/l) 5.9 ± 0.2 5.3 ± 0.2 6.1 ± 0.3 
Other parameters    
    fS insulin (mU/l) 12 ± 2 6 ± 1 15 ± 3 
    fS C-peptide (nmol/l) 0.9 ± 0.1 0.6 ± 0.1 1.1 ± 0.1 
    fS FFA (μmol/l) 588 ± 45 509 ± 90 628 ± 49 
    fS adiponectin (μg/ml) 9.7 ± 1 12.3 ± 2.1 8.4 ± 1§ 
    fP PAI-1 (ng/ml) 31 ± 3 24 ± 6 35 ± 3 
    fS LDL cholesterol (mmol/l) 2.7 ± 0.2 2.7 ± 0.3 2.7 ± 0.2 
    fS ALT (units/l) 87 ± 13 97 ± 21 82 ± 17 
    fS AST (units/l) 53 ± 6 55 ± 9 53 ± 8 
    MCV (fl) 90 ± 1 90 ± 1 90 ± 1 
    Daily alcohol dose 0.5 ± 0.2 0.4 ± 0.2 0.5 ± 0.2 

Data are means ± SE.

*

P < 0.001,

P < 0.05,

P < 0.01,

§

0.1 > P > 0.05, for subjects without (NAFL−) versus with (NAFL+) NAFLD. ALT, alanine aminotransferase; ASP, aspartate aminotransferase; fP, fasting plasma, fS, fasting serum; MCV, mean corpuscular volume; MetS, metabolic syndrome; NA, not applicable.

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