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TABLE 2

Characteristics of clusters identified by SPM at statistical threshold of P < 0.001

Cluster sizeT (peak value in cluster)P (corrected cluster level)xyz
Increased uptake (across both groups)       
    Left ventral striatum 749 16.65 8.3e-7 −22 
    Right ventral striatum 686 9.89 2.1e-6 18 12 
    Occipital cortex 2,008 8.94 1.5e-13 −81 17 
Decreased uptake (across both groups)       
    White matter 20,570 17.75 20 28 13 
    Left inferior frontal gyrus 313 9.45 0.0013 −55 25 
    Right inferior frontal gyrus 356 8.46 0.00057 59 17 −1 
    Right anterior white matter* 845 17.75 1.0e-14 20 28 13 
    Right periventricular white matter* 2,646 16.30 24 −31 38 
    Brainstem* 2,427 16.27 −7 −16 
    Left periventricular white matter* 4,864 14.75 −16 −35 29 
    Left inferior frontal gyrus* 119 9.45 0.00041 −55 25 
Greater increase in aware than in unaware subjects       
    Occipital cortex 365 6.60 0.0004 −2 −93 
    Left amygdala 305 6.65 NS −30 −15 
    Occipital cortex 1,851 6.60 6.5e-5 −2 −93 
    Left ventral striatum 196 5.54 NS −24 
    Left cerebellum 191 5.24 NS −46 −46 −21 
    Medial cerebellum/brainstem 2,861 5.24 6.8e-7 −42 −18 
Greater decrease in aware than in unaware subjects       
    Brodmann areas 10, 11, and 47 (right) 1,071 5.48 0.0041 36 32 −13 
    Brodmann areas 10, 45, and 46 (right) 414 4.37 NS 51 30 17 
    Brodmann areas 8 and 9 (right) 214 4.22 NS 24 23 41 
Cluster sizeT (peak value in cluster)P (corrected cluster level)xyz
Increased uptake (across both groups)       
    Left ventral striatum 749 16.65 8.3e-7 −22 
    Right ventral striatum 686 9.89 2.1e-6 18 12 
    Occipital cortex 2,008 8.94 1.5e-13 −81 17 
Decreased uptake (across both groups)       
    White matter 20,570 17.75 20 28 13 
    Left inferior frontal gyrus 313 9.45 0.0013 −55 25 
    Right inferior frontal gyrus 356 8.46 0.00057 59 17 −1 
    Right anterior white matter* 845 17.75 1.0e-14 20 28 13 
    Right periventricular white matter* 2,646 16.30 24 −31 38 
    Brainstem* 2,427 16.27 −7 −16 
    Left periventricular white matter* 4,864 14.75 −16 −35 29 
    Left inferior frontal gyrus* 119 9.45 0.00041 −55 25 
Greater increase in aware than in unaware subjects       
    Occipital cortex 365 6.60 0.0004 −2 −93 
    Left amygdala 305 6.65 NS −30 −15 
    Occipital cortex 1,851 6.60 6.5e-5 −2 −93 
    Left ventral striatum 196 5.54 NS −24 
    Left cerebellum 191 5.24 NS −46 −46 −21 
    Medial cerebellum/brainstem 2,861 5.24 6.8e-7 −42 −18 
Greater decrease in aware than in unaware subjects       
    Brodmann areas 10, 11, and 47 (right) 1,071 5.48 0.0041 36 32 −13 
    Brodmann areas 10, 45, and 46 (right) 414 4.37 NS 51 30 17 
    Brodmann areas 8 and 9 (right) 214 4.22 NS 24 23 41 

Clusters of voxels reaching significance, P < 0.001 (uncorrected) and minimum cluster size of 100 voxels (unless otherwise stated). T is peak t statistic within cluster; P is corrected for the cluster (not the voxel). Coordinates of the peak voxel are given in Talairach space.

*

Threshold of P < 0.0001, cluster size >100;

P < 0.01, cluster size >100. NS, not significant.

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