American Diabetes Association

TABLE 3

Haplotype association analysis of three selected PTPN22 SNPs

Haplotype	SNP					Haplotype frequency
Haplotype		rs3789604 (SNP37)^*	rs2476601 (C1858T)	rs2488457 (−1123)^†	Control subjects	Case subjects	P value
1	A	C	C	0.614	0.570	0.025
2	C	C	C	0.170	0.173	0.885
3	A	T	G	0.093	0.156	<10⁻⁶
4	A	C	G	0.119	0.094	0.044

Haplotype	SNP					Haplotype frequency
Haplotype		rs3789604 (SNP37)^*	rs2476601 (C1858T)	rs2488457 (−1123)^†	Control subjects	Case subjects	P value
1	A	C	C	0.614	0.570	0.025
2	C	C	C	0.170	0.173	0.885
3	A	T	G	0.093	0.156	<10⁻⁶
4	A	C	G	0.119	0.094	0.044

Other rare haplotypes had an overall frequency <0.01 and are not shown in this table.

*

Carlton et al. (12).

†

Kawasaki et al. (13).