Meta-analysis of the association between SNPs g.+45T→G and g.+276G→T and BMI
| Marker . | Study (ref.) . | Subjects (n) . | WMD (95% CI) . | WMD (95% CI) . | P . | P (hetero-geneity) . | P (publica-tion bias) . |
|---|---|---|---|---|---|---|---|
| g.+45T→G | T/G vs. T/T | G/G vs. T/T | |||||
| Fumeron (36)* | 4,448 | 0.20 (−0.07 to 0.47) | −0.20 (−1.15 to 0.75) | ||||
| Jang (41)† | 902 | −0.10 (−0.57 to 0.37) | −0.30 (−1.09 to 0.49) | ||||
| Kang (80)† | 166 | 0.80 (−0.14 to 1.74) | 0.10 (−1.11 to 1.31) | ||||
| Lee (43)† | 427 | −0.30 (−0.92 to 0.32) | −0.40 (−1.16 to 0.36) | ||||
| Menzaghi (45)* | 399 | −0.70 (−1.60 to 0.20) | −0.40 (−2.37 to 1.57) | ||||
| Nakatani (46)† | 194 | 0.80 (−0.12 to 1.72) | 1.54 (−0.04 to 3.12) | ||||
| Stumvoll (51)* | 371 | 1.40 (−0.09 to 2.89) | 2.30 (−0.31 to 4.91) | ||||
| Tanko (81)* | 1,380 | 0.00 (−0.51 to 0.51) | −0.80 (−3.12 to 1.52) | ||||
| Yang (82)† | 245 | −1.41 (−3.26 to 0.44) | −3.35 (−6.00 to −0.70) | ||||
| T/G vs. T/T | 8,287 | 0.09 (−0.09 to 0.28) | 0.32 | 0.046 | 0.53 | ||
| G/G vs. T/T | −0.18 (−0.58 to 0.23) | 0.39 | 0.07 | 0.95 | |||
| g.+276G→T | G/T vs. G/G | T/T vs. G/G | |||||
| Jang (41)† | 902 | −0.10 (−0.57 to 0.37) | 0.20 (−0.64 to 1.04) | ||||
| Kang (80)† | 166 | 0.00 (−0.80 to 0.80) | 0.00 (−1.29 to −1.29) | ||||
| Lee (43)† | 427 | 0.50 (−0.12 to 1.12) | 0.40 (−0.73 to 1.53) | ||||
| Mousavinasab (65)* | 252 | 0.20 (−0.89 to 1.29) | 1.10 (−0.77 to 2.97) | ||||
| Menzaghi (45)* | 403 | −1.30 (−2.21 to −0.39) | −1.20 (−2.49 to 0.09) | ||||
| Nakatani (46)† | 194 | −0.98 (−1.92 to −0.04) | −1.79 (−2.95 to −0.63) | ||||
| Tanko (81)* | 1,377 | 0.20 (−0.22 to 0.62) | −0.10 (−0.82 to 0.62) | ||||
| Ukkola (52)* | 95 | 2.10 (0.69–3.51) | 0.20 (−2.09 to 2.49) | ||||
| G/T vs. G/G | 3,816 | −0.01 (−0.59 to 0.57) | 0.98 | 0.001 | 0.60 | ||
| T/T vs. G/G | −0.15 (−0.80 to 0.50) | 0.65 | 0.06 | 0.69 |
| Marker . | Study (ref.) . | Subjects (n) . | WMD (95% CI) . | WMD (95% CI) . | P . | P (hetero-geneity) . | P (publica-tion bias) . |
|---|---|---|---|---|---|---|---|
| g.+45T→G | T/G vs. T/T | G/G vs. T/T | |||||
| Fumeron (36)* | 4,448 | 0.20 (−0.07 to 0.47) | −0.20 (−1.15 to 0.75) | ||||
| Jang (41)† | 902 | −0.10 (−0.57 to 0.37) | −0.30 (−1.09 to 0.49) | ||||
| Kang (80)† | 166 | 0.80 (−0.14 to 1.74) | 0.10 (−1.11 to 1.31) | ||||
| Lee (43)† | 427 | −0.30 (−0.92 to 0.32) | −0.40 (−1.16 to 0.36) | ||||
| Menzaghi (45)* | 399 | −0.70 (−1.60 to 0.20) | −0.40 (−2.37 to 1.57) | ||||
| Nakatani (46)† | 194 | 0.80 (−0.12 to 1.72) | 1.54 (−0.04 to 3.12) | ||||
| Stumvoll (51)* | 371 | 1.40 (−0.09 to 2.89) | 2.30 (−0.31 to 4.91) | ||||
| Tanko (81)* | 1,380 | 0.00 (−0.51 to 0.51) | −0.80 (−3.12 to 1.52) | ||||
| Yang (82)† | 245 | −1.41 (−3.26 to 0.44) | −3.35 (−6.00 to −0.70) | ||||
| T/G vs. T/T | 8,287 | 0.09 (−0.09 to 0.28) | 0.32 | 0.046 | 0.53 | ||
| G/G vs. T/T | −0.18 (−0.58 to 0.23) | 0.39 | 0.07 | 0.95 | |||
| g.+276G→T | G/T vs. G/G | T/T vs. G/G | |||||
| Jang (41)† | 902 | −0.10 (−0.57 to 0.37) | 0.20 (−0.64 to 1.04) | ||||
| Kang (80)† | 166 | 0.00 (−0.80 to 0.80) | 0.00 (−1.29 to −1.29) | ||||
| Lee (43)† | 427 | 0.50 (−0.12 to 1.12) | 0.40 (−0.73 to 1.53) | ||||
| Mousavinasab (65)* | 252 | 0.20 (−0.89 to 1.29) | 1.10 (−0.77 to 2.97) | ||||
| Menzaghi (45)* | 403 | −1.30 (−2.21 to −0.39) | −1.20 (−2.49 to 0.09) | ||||
| Nakatani (46)† | 194 | −0.98 (−1.92 to −0.04) | −1.79 (−2.95 to −0.63) | ||||
| Tanko (81)* | 1,377 | 0.20 (−0.22 to 0.62) | −0.10 (−0.82 to 0.62) | ||||
| Ukkola (52)* | 95 | 2.10 (0.69–3.51) | 0.20 (−2.09 to 2.49) | ||||
| G/T vs. G/G | 3,816 | −0.01 (−0.59 to 0.57) | 0.98 | 0.001 | 0.60 | ||
| T/T vs. G/G | −0.15 (−0.80 to 0.50) | 0.65 | 0.06 | 0.69 |
Race/ethnicity:
Caucasian,
Asian.