American Diabetes Association

TABLE 3

Summary statistics of parameters in the GEM fits and age at which the exponential effect has contributed various amounts of excess glucose with corresponding years to onset as estimated by the GEM on the study participants

	Minimum	25th	Median	75th	Maximum
a (mg/dl per year)	−5.99	−0.44	0.75	1.51	2.69
b (mg/dl)	45.89	70.38	93.03	110.53	316.50
c (year⁻¹)	0.08	0.36	0.55	1.76	184.25
d (years)	−6.80	28.72	35.85	42.28	64.37
Age exp Δ = 10 mg/dl (years)^*	19.20	34.72	40.21	43.93	66.48
Time to onset (years)^†	0.01	1.16	4.15	9.17	42.10
Age exp Δ = 20 mg/dl (years)^‡	21.83	35.50	41.34	45.19	67.12
Time to onset (years)^§	0.01	0.52	2.97	7.01	33.32

	Minimum	25th	Median	75th	Maximum
a (mg/dl per year)	−5.99	−0.44	0.75	1.51	2.69
b (mg/dl)	45.89	70.38	93.03	110.53	316.50
c (year⁻¹)	0.08	0.36	0.55	1.76	184.25
d (years)	−6.80	28.72	35.85	42.28	64.37
Age exp Δ = 10 mg/dl (years)^*	19.20	34.72	40.21	43.93	66.48
Time to onset (years)^†	0.01	1.16	4.15	9.17	42.10
Age exp Δ = 20 mg/dl (years)^‡	21.83	35.50	41.34	45.19	67.12
Time to onset (years)^§	0.01	0.52	2.97	7.01	33.32

n = 55.

Age at which the second effect {G₀ · exp[c(t − d)]} contributes 10 mg/dl;

†

years until diabetes diagnosis from *;

‡

age at which the second effect {G₀ · exp[c(t − d)]} contributes 20 mg/dl;

years until diabetes diagnosis from ‡.

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