American Diabetes Association

Skip to Main Content

TABLE 3

Insulitis, β-cell surface area, and β-cell proliferation in aAb⁺ organ donors

No. of aAbs	Case subject	No. of islets with insulitis/total islets examined	Relative β-cell surface area [% (range)]	Ki67⁺ INS⁺ cells/INS⁺ cells ‰ (range)
4	1	5/58	1.95	49^*/0†
3	2	27/917	1.59	0
	3	0/99	1.46	0
2	4	0/116	1.50	0
	5	0/137	0.82	0
	6	0/141	0.79	0
	7	0/331	1.28	0
1	n = 55	0/10,223	1.13 (0.50–2.80)	0.4 (0–5)
0	n = 62	0/10,334	1.21 (0.51–2.61)	0.4 (0–7)

No. of aAbs	Case subject	No. of islets with insulitis/total islets examined	Relative β-cell surface area [% (range)]	Ki67⁺ INS⁺ cells/INS⁺ cells ‰ (range)
4	1	5/58	1.95	49^*/0†
3	2	27/917	1.59	0
	3	0/99	1.46	0
2	4	0/116	1.50	0
	5	0/137	0.82	0
	6	0/141	0.79	0
	7	0/331	1.28	0
1	n = 55	0/10,223	1.13 (0.50–2.80)	0.4 (0–5)
0	n = 62	0/10,334	1.21 (0.51–2.61)	0.4 (0–7)

*

Ki67⁺ ins⁺ cell number in islets with insulitis. †Ki67⁺ ins⁺ cell number in islets with no signs of insulitis.