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TABLE 2

Circulating arterialized metabolite concentrations during baseline and isoprenaline infusion in lean and obese subjects

Lean
Obese
BaselineISOΔBaselineISOΔ
n 13 10 10 10 
TAG (μmol/l) 701 ± 66 648 ± 64* −46 ± 23 1,464 ± 190 1,667 ± 217* 112 ± 44 
FFA (μmol/l) 661 ± 41 942 ± 53* 271 ± 46 638 ± 42 1,124 ± 82* 469 ± 82 
Glycerol (μmol/l) 102 ± 5 118 ± 7* 15 ± 5 106 ± 4 147 ± 10* 44 ± 9 
Glycerol Ra (μmol/min) 199 ± 12 311 ± 28* 109 ± 13 220 ± 15 391 ± 30* 172 ± 19 
Glycerol Ra/FFM (μmol · kg−1 FFM · min−13.4 ± 0.2 5.5 ± 0.5* 2.0 ± 0.5 3.3 ± 0.3 5.8 ± 0.6* 2.5 ± 0.5 
Glucose (mmol/l) 5.3 ± 0.1 5.4 ± 0.1 0.14 ± 0.06 5.5 ± 0.2 5.4 ± 0.1 −0.12 ± 0.10 
Insulin (mU/l) 7.2 ± 0.6 10.7 ± 0.9* 3.4 ± 0.6 13.6 ± 1.0 24.0 ± 2.3* 10.6 ± 1.5 
Lactate (mmol/l) 0.61 ± 0.04 0.72 ± 0.03 0.09 ± 0.04 0.98 ± 0.11 0.99 ± 0.06 0.05 ± 0.07 
Lean
Obese
BaselineISOΔBaselineISOΔ
n 13 10 10 10 
TAG (μmol/l) 701 ± 66 648 ± 64* −46 ± 23 1,464 ± 190 1,667 ± 217* 112 ± 44 
FFA (μmol/l) 661 ± 41 942 ± 53* 271 ± 46 638 ± 42 1,124 ± 82* 469 ± 82 
Glycerol (μmol/l) 102 ± 5 118 ± 7* 15 ± 5 106 ± 4 147 ± 10* 44 ± 9 
Glycerol Ra (μmol/min) 199 ± 12 311 ± 28* 109 ± 13 220 ± 15 391 ± 30* 172 ± 19 
Glycerol Ra/FFM (μmol · kg−1 FFM · min−13.4 ± 0.2 5.5 ± 0.5* 2.0 ± 0.5 3.3 ± 0.3 5.8 ± 0.6* 2.5 ± 0.5 
Glucose (mmol/l) 5.3 ± 0.1 5.4 ± 0.1 0.14 ± 0.06 5.5 ± 0.2 5.4 ± 0.1 −0.12 ± 0.10 
Insulin (mU/l) 7.2 ± 0.6 10.7 ± 0.9* 3.4 ± 0.6 13.6 ± 1.0 24.0 ± 2.3* 10.6 ± 1.5 
Lactate (mmol/l) 0.61 ± 0.04 0.72 ± 0.03 0.09 ± 0.04 0.98 ± 0.11 0.99 ± 0.06 0.05 ± 0.07 

Data are means ± SE.

*

P < 0.05 ISO vs. baseline.

P < 0.05 obese vs. lean.

P < 0.05 change (Δ) from baseline obese vs. lean.

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