American Diabetes Association

TABLE 3

Regional forearm blood flow and net metabolite flux during baseline and isoprenaline infusion in lean and obese subjects

	Lean			Obese
	Baseline	ISO	Baseline	ISO
n	13	10	10	7
FBF (ml · 100 ml⁻¹ tissue · min⁻¹)	2.9 ± 0.2	4.6 ± 0.4^*	2.5 ± 0.3	3.5 ± 0.3^*
Forearm net flux (nmol · 100 ml⁻¹ tissue · min⁻¹)
TAG	17 ± 5	24 ± 19^†	−2 ± 9^†	46 ± 31^†
FFA	6 ± 59^†	−53 ± 143^†	156 ± 42	230 ± 88
Glycerol	−21 ± 11^†	−39 ± 33^†	11 ± 5^†^‡	6 ± 21^†
Glucose	142 ± 51	213 ± 117^†	226 ± 81	289 ± 223^†
Lactate	−90 ± 27	−171 ± 73	8 ± 45	−327 ± 78

	Lean			Obese
	Baseline	ISO	Baseline	ISO
n	13	10	10	7
FBF (ml · 100 ml⁻¹ tissue · min⁻¹)	2.9 ± 0.2	4.6 ± 0.4^*	2.5 ± 0.3	3.5 ± 0.3^*
Forearm net flux (nmol · 100 ml⁻¹ tissue · min⁻¹)
TAG	17 ± 5	24 ± 19^†	−2 ± 9^†	46 ± 31^†
FFA	6 ± 59^†	−53 ± 143^†	156 ± 42	230 ± 88
Glycerol	−21 ± 11^†	−39 ± 33^†	11 ± 5^†^‡	6 ± 21^†
Glucose	142 ± 51	213 ± 117^†	226 ± 81	289 ± 223^†
Lactate	−90 ± 27	−171 ± 73	8 ± 45	−327 ± 78

Data are means ± SE. Positive flux = net uptake; negative flux = net release.

P < 0.05 ISO vs. baseline.

†

Exchange not different from zero.

‡

P < 0.05 obese vs. lean.