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TABLE 1

Result of embryonic phenotype analysis and complementation tests

Heterozygous crossStage (dpc)Affected embryos (two mutant alleles)Unaffected embryos (two mutant alleles)Unaffected embryos (wild-type alleles)
S70P X Y123C 9.5 
S70P X Y123C 13.5 18 
Y123C X Y123C 9.5 16 
Y123C X Y123C 14.5 
Del X Y123C 13.5 
Heterozygous crossStage (dpc)Affected embryos (two mutant alleles)Unaffected embryos (two mutant alleles)Unaffected embryos (wild-type alleles)
S70P X Y123C 9.5 
S70P X Y123C 13.5 18 
Y123C X Y123C 9.5 16 
Y123C X Y123C 14.5 
Del X Y123C 13.5 

Data are n. Males heterozygous for the Y123C Sox4 mutation were crossed to females heterozygous for the same mutation, the S70P mutation, and the Del(13)Svea36H deletion. Embryo dissections were carried out at 9.5, 13.5, and 14.5 dpc, and the embryonic phenotype was visually analyzed.

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