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TABLE 2

Pancreatic islet area in 17-week-old male mice

GenotypeTotal sectional area*Total islet area*Islets (n)Islet area (%)
Sox4 Y123C 6,707,744 76,493 173 1.14 
Sox4 Y123C 4,582,464 56,548 124 1.23 
Sox4 Y123C 7,077,281 141,769 199 2.00 
Total 18,367,489 274,810 496 1.50 
Wild-type littermate 6,960,257 138,588 245 1.99 
Wild-type littermate 6,163,259 58,314 170 0.95 
Wild-type littermate 5,752,898 97,481 151 1.69 
Total 18,876,414 294,383 566 1.56 
GenotypeTotal sectional area*Total islet area*Islets (n)Islet area (%)
Sox4 Y123C 6,707,744 76,493 173 1.14 
Sox4 Y123C 4,582,464 56,548 124 1.23 
Sox4 Y123C 7,077,281 141,769 199 2.00 
Total 18,367,489 274,810 496 1.50 
Wild-type littermate 6,960,257 138,588 245 1.99 
Wild-type littermate 6,163,259 58,314 170 0.95 
Wild-type littermate 5,752,898 97,481 151 1.69 
Total 18,876,414 294,383 566 1.56 

Data are n and percent. The pancreas was mounted longitudinally and serially sectioned with every 20th section stained with H-E, resulting in 10 sections from each of 3 mutant mice (Sox4Y123C) and 3 wild-type mice (60 whole sections).

*

Arbitrary units based on pixel values.

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