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TABLE 1

Clinical characteristics of male study participants before and after bed rest

Before bed rest
After bed rest
FDR groupCON groupFDR groupCON group
n 13 20 13 20 
Age (years) 26.4 ± 4.4 25.0 ± 1.0 26.4 ± 4.4 25.0 ± 1.0 
Weight (kg) 84.0 ± 11.7 82.5 ± 10.1 83.6 ± 11.6 82.2 ± 10.4 
Height (m) 1.84 ± 0.06 1.85 ± 0.05 1.84 ± 0.06 1.85 ± 0.05 
FFM (kg) 58.6 ± 5.4 63.8 ± 4.7 58.4 ± 5.5 63.6 ± 4.8 
BMI (kg/m2) 24.9 ± 3.1 24.1 ± 2.3 24.8 ± 3.1 23.9 ± 2.4 
Vo2max (ml · min−1 · kg−139.1 ± 6.7 43.5 ± 6.0 37.5 ± 6.6 42.8 ± 4.9 
Systolic blood pressure (mmHg) 126 ± 11 128 ± 11 128 ± 8 126 ± 9 
Diastolic blood pressure (mmHg) 71 ± 10 68 ± 3 71 ± 8 70 ± 7 
Waist-to-hip ratio 0.88 ± 0.06 0.85 ± 0.04 0.87 ± 0.06 0.86 ± 0.04 
Total FM (kg) 21.7 ± 9.1 14.3 ± 7.5* 21.5 ± 9.6 14.5 ± 7.8 
Whole-body fat percentage (%) 25.0 ± 8.3 16.9 ± 7.0* 24.9 ± 9.0 17.1 ± 7.3 
Trunk FM–to–total FM ratio 0.58 ± 0.03 0.48 ± 0.04* 0.58 ± 0.04 0.49 ± 0.04 
Leg FM–to–total FM ratio 0.29 ± 0.04 0.37 ± 0.02* 0.29 ± 0.04 0.37 ± 0.03 
% trunk FM–to–leg FM ratio 2.06 ± 0.37 1.31 ± 0.18* 2.07 ± 0.45 1.33 ± 0.22 
Triglycerides (mmol/l) 1.1 ± 0.4 0.9 ± 0.4 1.3 ± 0.5 1.0 ± 0.5§ 
Total cholesterol (mmol/l) 4.5 ± 1.0 3.9 ± 0.8 4.4 ± 0.8 3.7 ± 0.9§ 
HDL cholesterol (mmol/l) 1.2 ± 0.3 1.2 ± 0.3 1.1 ± 0.3 1.1 ± 0.3 
LDL cholesterol (mmol/l) 2.8 ± 0.3 2.2 ± 0.7 2.7 ± 0.7 2.0 ± 0.5 
VLDL cholesterol (mmol/l) 0.5 ± 0.2 0.4 ± 0.2 0.6 ± 0.2 0.4 ± 0.2 
A1C (%) 5.1 ± 0.3 5.1 ± 0.2 NM NM 
Before bed rest
After bed rest
FDR groupCON groupFDR groupCON group
n 13 20 13 20 
Age (years) 26.4 ± 4.4 25.0 ± 1.0 26.4 ± 4.4 25.0 ± 1.0 
Weight (kg) 84.0 ± 11.7 82.5 ± 10.1 83.6 ± 11.6 82.2 ± 10.4 
Height (m) 1.84 ± 0.06 1.85 ± 0.05 1.84 ± 0.06 1.85 ± 0.05 
FFM (kg) 58.6 ± 5.4 63.8 ± 4.7 58.4 ± 5.5 63.6 ± 4.8 
BMI (kg/m2) 24.9 ± 3.1 24.1 ± 2.3 24.8 ± 3.1 23.9 ± 2.4 
Vo2max (ml · min−1 · kg−139.1 ± 6.7 43.5 ± 6.0 37.5 ± 6.6 42.8 ± 4.9 
Systolic blood pressure (mmHg) 126 ± 11 128 ± 11 128 ± 8 126 ± 9 
Diastolic blood pressure (mmHg) 71 ± 10 68 ± 3 71 ± 8 70 ± 7 
Waist-to-hip ratio 0.88 ± 0.06 0.85 ± 0.04 0.87 ± 0.06 0.86 ± 0.04 
Total FM (kg) 21.7 ± 9.1 14.3 ± 7.5* 21.5 ± 9.6 14.5 ± 7.8 
Whole-body fat percentage (%) 25.0 ± 8.3 16.9 ± 7.0* 24.9 ± 9.0 17.1 ± 7.3 
Trunk FM–to–total FM ratio 0.58 ± 0.03 0.48 ± 0.04* 0.58 ± 0.04 0.49 ± 0.04 
Leg FM–to–total FM ratio 0.29 ± 0.04 0.37 ± 0.02* 0.29 ± 0.04 0.37 ± 0.03 
% trunk FM–to–leg FM ratio 2.06 ± 0.37 1.31 ± 0.18* 2.07 ± 0.45 1.33 ± 0.22 
Triglycerides (mmol/l) 1.1 ± 0.4 0.9 ± 0.4 1.3 ± 0.5 1.0 ± 0.5§ 
Total cholesterol (mmol/l) 4.5 ± 1.0 3.9 ± 0.8 4.4 ± 0.8 3.7 ± 0.9§ 
HDL cholesterol (mmol/l) 1.2 ± 0.3 1.2 ± 0.3 1.1 ± 0.3 1.1 ± 0.3 
LDL cholesterol (mmol/l) 2.8 ± 0.3 2.2 ± 0.7 2.7 ± 0.7 2.0 ± 0.5 
VLDL cholesterol (mmol/l) 0.5 ± 0.2 0.4 ± 0.2 0.6 ± 0.2 0.4 ± 0.2 
A1C (%) 5.1 ± 0.3 5.1 ± 0.2 NM NM 

Data are means ± SD.

*Significant difference between FDR and CON groups before bed rest, P < 0.05.

†Significant difference between FDR and CON groups after bed rest, P < 0.05.

‡Log-transformed data.

§P = 0.05 between FDR and CON groups after bed rest.

‖Significant difference before vs. after bed rest; P < 0.05. NM, not measured.

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