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TABLE 3

Results from homeostasis model assessment of insulin resistance, peripheral and hepatic insulin secretion disposition index (Di-peripheral and Di-hepatic)

Before bed rest
After bed rest
FDR groupCON groupFDR groupCON group
n 13 20 13 20 
Basal HOMA-IR* 1.0 ± 0.3 0.8 ± 0.3 1.6 ± 0.7 1.1 ± 0.5 
Di-peripheral (10−3 × pmol · l−1 · min−1 · mg−1 · min−1 · kg FFM−1)* 28.9 ± 20.9 27.4 ± 15.9 34.8 ± 33.5 32.7 ± 17.6 
Di-hepatic (pmol · l−1 · min−1 · μmol−1 · min−1 · kg FFM−1 · pmol−1 · l−1)* 4.1 ± 1.8 11.5 ± 16.9§ 4.5 ± 2.9 9.6 ± 6.3 
Before bed rest
After bed rest
FDR groupCON groupFDR groupCON group
n 13 20 13 20 
Basal HOMA-IR* 1.0 ± 0.3 0.8 ± 0.3 1.6 ± 0.7 1.1 ± 0.5 
Di-peripheral (10−3 × pmol · l−1 · min−1 · mg−1 · min−1 · kg FFM−1)* 28.9 ± 20.9 27.4 ± 15.9 34.8 ± 33.5 32.7 ± 17.6 
Di-hepatic (pmol · l−1 · min−1 · μmol−1 · min−1 · kg FFM−1 · pmol−1 · l−1)* 4.1 ± 1.8 11.5 ± 16.9§ 4.5 ± 2.9 9.6 ± 6.3 

Data are means ± SD.

*Log-transformed data.

†Significant difference before vs. after bed rest; P < 0.05.

‡Significant difference between FDR and CON groups after bed rest, P < 0.05.

§Significant difference between FDR and CON groups before bed rest, P < 0.05. Di-hepatic, measure for hepatic insulin action; Di-peripheral, peripheral disposition index, measure for peripheral insulin action; HOMA-IR, homeostasis model assessment of insulin resistance.

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