Skip to Main Content
TABLE 7

Association results of top 13 SNPs from DCCT with A1C in the MAGIC study of nondiabetic individuals

ChromosomePositionSNPAllele 1Allele 2EffectSEPSample size
BNC2 gene region         
    9 16,779,024 rs10810632 −0.0220 0.0065 7.1 × 10−4 36,446 
    9 16,779,436 rs6475082 −0.0235 0.0064 2.7 × 10−4 36,557 
    9 16,779,878 rs4961760 −0.0194 0.0065 0.0030 35,837 
    9 16,791,850 rs2254193 −0.0235 0.0066 3.5 × 10−4 36,458 
SORCS1 gene region         
    10 108,113,589 rs1358030 0.0014 0.0036 0.70 35,304 
GSC gene region         
    14 94,375,765 rs11624318 0.0016 0.0042 0.71 35,801 
    14 94,405,244 rs11160219 −0.0018 0.0044 0.68 32,898 
    14 94,407,241 rs8007115 −0.0012 0.0045 0.79 27,589 
WDR72 gene region         
    15 51,277,554 rs493218 −0.0015 0.0057 0.79 36,530 
    15 51,291,924 rs572221 0.0015 0.0057 0.79 36,561 
    15 51,291,964 rs690271 0.0014 0.0057 0.81 36,585 
    15 51,295,884 rs566369 0.0012 0.0057 0.83 36,575 
    15 51,296,486 rs482541 0.0010 0.0057 0.86 36,577 
    18 22,727,740 rs163061 −0.0048 0.0041 0.25 33,297 
ChromosomePositionSNPAllele 1Allele 2EffectSEPSample size
BNC2 gene region         
    9 16,779,024 rs10810632 −0.0220 0.0065 7.1 × 10−4 36,446 
    9 16,779,436 rs6475082 −0.0235 0.0064 2.7 × 10−4 36,557 
    9 16,779,878 rs4961760 −0.0194 0.0065 0.0030 35,837 
    9 16,791,850 rs2254193 −0.0235 0.0066 3.5 × 10−4 36,458 
SORCS1 gene region         
    10 108,113,589 rs1358030 0.0014 0.0036 0.70 35,304 
GSC gene region         
    14 94,375,765 rs11624318 0.0016 0.0042 0.71 35,801 
    14 94,405,244 rs11160219 −0.0018 0.0044 0.68 32,898 
    14 94,407,241 rs8007115 −0.0012 0.0045 0.79 27,589 
WDR72 gene region         
    15 51,277,554 rs493218 −0.0015 0.0057 0.79 36,530 
    15 51,291,924 rs572221 0.0015 0.0057 0.79 36,561 
    15 51,291,964 rs690271 0.0014 0.0057 0.81 36,585 
    15 51,295,884 rs566369 0.0012 0.0057 0.83 36,575 
    15 51,296,486 rs482541 0.0010 0.0057 0.86 36,577 
    18 22,727,740 rs163061 −0.0048 0.0041 0.25 33,297 

Allele 1 indicates the effect allele compared with allele 2 as the reference. Alleles are aligned to HapMap forward strand, but are not aligned in terms of minor or major allele. The A1C values were untransformed % [National Glycohemoglobin Standardization Program transformation: %A1C = 91.48 × (A1C/Hb) + 2.152], adjusted for age and sex.

Close Modal

or Create an Account

Close Modal
Close Modal