Prevalence rate of hyperglycemia by birth cohorts and severity of famine areas: sensitivity analyses
| . | Childhood-exposed cohorts . | Fetal-exposed cohort . | Nonexposed cohort . | ||
|---|---|---|---|---|---|
| Late childhood . | Mid childhood . | Early childhood . | |||
| Defining severity of famine by excess death rate ≥100% | |||||
| Severely affected famine area | |||||
| Prevalence (%) | 3.92 | 2.56 | 2.60 | 8.11 | 1.39 |
| Odds ratio (95% CI) | 2.15 (0.90–5.14) | 1.56 (0.62–3.88) | 1.80 (0.66–4.92) | 6.28 (2.16–18.3) | |
| Less severely affected famine area | |||||
| Prevalence (%) | 7.92 | 4.42 | 5.32 | 3.39 | 3.74 |
| Odds ratio (95% CI) | 2.54 (1.24–5.20) | 1.33 (0.62–2.88) | 1.40 (0.68–2.88) | 0.89 (0.42–1.90) | |
| P for interaction between area and cohort | 0.492 | 0.373 | 0.362 | 0.003 | |
| Classifying adults born during October 1, 1962, to September 30, 1968, as nonexposed cohort | |||||
| Severely affected famine area | |||||
| Prevalence (%) | 5.19 | 2.68 | 3.76 | 7.29 | 3.11 |
| Odds ratio (95%CI) | 2.18 (1.21–3.93) | 1.10 (0.59–2.03) | 1.51 (0.79–2.87) | 3.38 (1.55–7.36) | |
| Less severely affected famine area | |||||
| Prevalence (%) | 7.17 | 5.22 | 4.34 | 2.14 | 2.33 |
| Odds ratio (95% CI) | 2.47 (1.34–4.53) | 1.83 (0.86–3.91) | 1.30 (0.74–2.30) | 0.61 (0.30–1.26) | |
| P for interaction between area and cohort | 0.966 | 0.395 | 0.693 | 0.001 | |
| Excluding people with family history of diabetes | |||||
| Severely affected famine area | |||||
| Prevalence (%) | 5.06 | 2.64 | 3.51 | 7.08 | 1.98 |
| Odds ratio (95% CI) | 2.40 (1.10–5.22) | 1.23 (0.57–2.63) | 1.73 (0.78–3.86) | 4.00 (1.64–9.73) | |
| Less severely affected famine area | |||||
| Prevalence (%) | 6.03 | 5.02 | 3.93 | 2.16 | 3.10 |
| Odds ratio (95% CI) | 2.41 (1.00–5.81) | 1.83 (0.71–4.70) | 1.30 (0.61–2.77) | 0.67 (0.29–1.563) | |
| P for interaction between area and cohort | 0.505 | 0.826 | 0.488 | 0.003 | |
| . | Childhood-exposed cohorts . | Fetal-exposed cohort . | Nonexposed cohort . | ||
|---|---|---|---|---|---|
| Late childhood . | Mid childhood . | Early childhood . | |||
| Defining severity of famine by excess death rate ≥100% | |||||
| Severely affected famine area | |||||
| Prevalence (%) | 3.92 | 2.56 | 2.60 | 8.11 | 1.39 |
| Odds ratio (95% CI) | 2.15 (0.90–5.14) | 1.56 (0.62–3.88) | 1.80 (0.66–4.92) | 6.28 (2.16–18.3) | |
| Less severely affected famine area | |||||
| Prevalence (%) | 7.92 | 4.42 | 5.32 | 3.39 | 3.74 |
| Odds ratio (95% CI) | 2.54 (1.24–5.20) | 1.33 (0.62–2.88) | 1.40 (0.68–2.88) | 0.89 (0.42–1.90) | |
| P for interaction between area and cohort | 0.492 | 0.373 | 0.362 | 0.003 | |
| Classifying adults born during October 1, 1962, to September 30, 1968, as nonexposed cohort | |||||
| Severely affected famine area | |||||
| Prevalence (%) | 5.19 | 2.68 | 3.76 | 7.29 | 3.11 |
| Odds ratio (95%CI) | 2.18 (1.21–3.93) | 1.10 (0.59–2.03) | 1.51 (0.79–2.87) | 3.38 (1.55–7.36) | |
| Less severely affected famine area | |||||
| Prevalence (%) | 7.17 | 5.22 | 4.34 | 2.14 | 2.33 |
| Odds ratio (95% CI) | 2.47 (1.34–4.53) | 1.83 (0.86–3.91) | 1.30 (0.74–2.30) | 0.61 (0.30–1.26) | |
| P for interaction between area and cohort | 0.966 | 0.395 | 0.693 | 0.001 | |
| Excluding people with family history of diabetes | |||||
| Severely affected famine area | |||||
| Prevalence (%) | 5.06 | 2.64 | 3.51 | 7.08 | 1.98 |
| Odds ratio (95% CI) | 2.40 (1.10–5.22) | 1.23 (0.57–2.63) | 1.73 (0.78–3.86) | 4.00 (1.64–9.73) | |
| Less severely affected famine area | |||||
| Prevalence (%) | 6.03 | 5.02 | 3.93 | 2.16 | 3.10 |
| Odds ratio (95% CI) | 2.41 (1.00–5.81) | 1.83 (0.71–4.70) | 1.30 (0.61–2.77) | 0.67 (0.29–1.563) | |
| P for interaction between area and cohort | 0.505 | 0.826 | 0.488 | 0.003 | |
All odds ratios used the nonexposed cohort as the reference cohort. Adjusted factors include sex, educational level, family history of diabetes, and current smoking, alcohol use, and physical activity level in 2002.