Skip to Main Content
TABLE 2

Anthropometric and baseline metabolic characteristics by weight change at follow-up

Weight loser
Weight stable
Weight gainer
MenWomenMenWomenMenWomen
n 96 117 281 349 95 110 
Age (years)* 44 ± 9 46 ± 8 44 ± 9 45 ± 8 43 ± 8 44 ± 8 
Weight (kg)* 85 ± 11 71 ± 12 82 ± 12 65 ± 11 85 ± 14 70 ± 13 
BMI (kg/m2)* 26.8 ± 3.1 26.3 ± 4.3 25.7 ± 3.2 24.1 ± 3.9 26.7 ± 3.8 25.5 ± 4.3 
Fat mass (%)* 23 ± 6 35 ± 7 21 ± 6 31 ± 7 23 ± 7 34 ± 7 
Waist (cm)* 95 ± 9 85 ± 11 92 ± 10 80 ± 11 96 ± 11 84 ± 11 
NGT/IFG/IGT (%) 8/0/0 9/0/2 24/1/1 29/0/3 8/0/0 9/0/1 
Fasting glucose (mmol/L)* 5.23 ± 0.53 4.93 ± 0.6 5.21 ± 0.49 4.98 ± 0.51 5.12 ± 0.48 4.94 ± 0.70 
2-h glucose (mmol/L)* 5.18 ± 0.60 4.84 ± 0.58 5.13 ± 1.19 4.94 ± 0.75 5.12 ± 0.48 4.94 ± 0.70 
M (μmol ⋅ kgFFM−1 ⋅ min−1)* 48 [23] 55 [29] 49 [24] 60 [25] 44 [23] 53 [20] 
Steady-state plasma insulin (pmol/L) 407 [124] 397 [104] 397 [129] 393 [114] 409 [111] 390 [110] 
M/I (μmol ⋅ min−1 ⋅ kgFFM−1 ⋅ nM−1)* 110 [70] 137 [92] 116 [68] 154 [83] 103 [72] 138 [60] 
Fasting insulin SR (pmol ⋅ m−2 ⋅ min−1) 69 [33] 71 [38] 73 [41] 64 [34] 74 [44] 73 [36] 
Total insulin output (nmol ⋅ m−238 [18] 41 [15] 39 [17] 39 [17] 39 [21] 40 [15] 
Glucose sensitivity (pmol ⋅ m−2 ⋅ min−1 ⋅ mM−1)* 103 [68] 112 [100] 102 [68] 124 [92] 110 [64] 116 [87] 
Rate sensitivity (nmol ⋅ m−2 ⋅ mM−10.85 [1.1] 0.68 [1.08] 0.85 [1.2] 0.73 [1.31] 0.76 [1.29] 0.93 [1.2] 
Potentiation ratio 1.59 [1.18] 1.71 [1.29] 1.75 [1.21] 1.76 [1.35] 1.72 [1.15] 1.46 [1.18] 
AIR (pmol/L)* 127 [192]  86 [165] 89 [208] 93 [157] 128 [169] 104 [155] 
AIRCpep (pmol/L)* 791 [687] 696 [535] 743 [664] 609 [603] 838 [535] 677 [536] 
Insulinogenic index (pmol/mmol) 75 [77] 78 [80] 73 [62] 74 [77] 75 [61] 80 [61] 
Weight loser
Weight stable
Weight gainer
MenWomenMenWomenMenWomen
n 96 117 281 349 95 110 
Age (years)* 44 ± 9 46 ± 8 44 ± 9 45 ± 8 43 ± 8 44 ± 8 
Weight (kg)* 85 ± 11 71 ± 12 82 ± 12 65 ± 11 85 ± 14 70 ± 13 
BMI (kg/m2)* 26.8 ± 3.1 26.3 ± 4.3 25.7 ± 3.2 24.1 ± 3.9 26.7 ± 3.8 25.5 ± 4.3 
Fat mass (%)* 23 ± 6 35 ± 7 21 ± 6 31 ± 7 23 ± 7 34 ± 7 
Waist (cm)* 95 ± 9 85 ± 11 92 ± 10 80 ± 11 96 ± 11 84 ± 11 
NGT/IFG/IGT (%) 8/0/0 9/0/2 24/1/1 29/0/3 8/0/0 9/0/1 
Fasting glucose (mmol/L)* 5.23 ± 0.53 4.93 ± 0.6 5.21 ± 0.49 4.98 ± 0.51 5.12 ± 0.48 4.94 ± 0.70 
2-h glucose (mmol/L)* 5.18 ± 0.60 4.84 ± 0.58 5.13 ± 1.19 4.94 ± 0.75 5.12 ± 0.48 4.94 ± 0.70 
M (μmol ⋅ kgFFM−1 ⋅ min−1)* 48 [23] 55 [29] 49 [24] 60 [25] 44 [23] 53 [20] 
Steady-state plasma insulin (pmol/L) 407 [124] 397 [104] 397 [129] 393 [114] 409 [111] 390 [110] 
M/I (μmol ⋅ min−1 ⋅ kgFFM−1 ⋅ nM−1)* 110 [70] 137 [92] 116 [68] 154 [83] 103 [72] 138 [60] 
Fasting insulin SR (pmol ⋅ m−2 ⋅ min−1) 69 [33] 71 [38] 73 [41] 64 [34] 74 [44] 73 [36] 
Total insulin output (nmol ⋅ m−238 [18] 41 [15] 39 [17] 39 [17] 39 [21] 40 [15] 
Glucose sensitivity (pmol ⋅ m−2 ⋅ min−1 ⋅ mM−1)* 103 [68] 112 [100] 102 [68] 124 [92] 110 [64] 116 [87] 
Rate sensitivity (nmol ⋅ m−2 ⋅ mM−10.85 [1.1] 0.68 [1.08] 0.85 [1.2] 0.73 [1.31] 0.76 [1.29] 0.93 [1.2] 
Potentiation ratio 1.59 [1.18] 1.71 [1.29] 1.75 [1.21] 1.76 [1.35] 1.72 [1.15] 1.46 [1.18] 
AIR (pmol/L)* 127 [192]  86 [165] 89 [208] 93 [157] 128 [169] 104 [155] 
AIRCpep (pmol/L)* 791 [687] 696 [535] 743 [664] 609 [603] 838 [535] 677 [536] 
Insulinogenic index (pmol/mmol) 75 [77] 78 [80] 73 [62] 74 [77] 75 [61] 80 [61] 

Data are mean ± SD and median [interquartile range] unless otherwise indicated. SR, secretion rate; AIRCpep, acute insulin response as the C-peptide response.

*Significant for sex at P ≤ 0.05 or less.

†Significant for weight category at P ≤ 0.05 or less.

Close Modal

or Create an Account

Close Modal
Close Modal