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Table 6—

Summary of recommendations for adults with diabetes mellitus

Glycemic control  
    A1C <7.0%* 
    Preprandial plasma glucose 90–130 mg/dl (5.0–7.2 mmol/l) 
    Peak postprandial plasma glucose <180 mg/dl (<10.0 mmol/l) 
Blood pressure <130/80 mmHg 
Lipids  
    LDL <100 mg/dl (<2.6 mmol/l) 
    Triglycerides <150 mg/dl (<1.7 mmol/l) 
    HDL >40 mg/dl (>1.1 mmol/l) 
Key concepts in setting glycemic goals:  
    • Goals should be individualized  
    • Certain populations (children, pregnant women, and elderly) require special considerations  
    • Less intensive glycemic goals may be indicated in patients with severe or frequent hypoglycemia  
    • More intensive glycemic goals may further reduce microvascular complications at the cost of increasing hypoglycemia  
    • Postprandial glucose may be targeted if A1C goals are not met despite reaching preprandial glucose goals  
Glycemic control  
    A1C <7.0%* 
    Preprandial plasma glucose 90–130 mg/dl (5.0–7.2 mmol/l) 
    Peak postprandial plasma glucose <180 mg/dl (<10.0 mmol/l) 
Blood pressure <130/80 mmHg 
Lipids  
    LDL <100 mg/dl (<2.6 mmol/l) 
    Triglycerides <150 mg/dl (<1.7 mmol/l) 
    HDL >40 mg/dl (>1.1 mmol/l) 
Key concepts in setting glycemic goals:  
    • Goals should be individualized  
    • Certain populations (children, pregnant women, and elderly) require special considerations  
    • Less intensive glycemic goals may be indicated in patients with severe or frequent hypoglycemia  
    • More intensive glycemic goals may further reduce microvascular complications at the cost of increasing hypoglycemia  
    • Postprandial glucose may be targeted if A1C goals are not met despite reaching preprandial glucose goals  
*

Referenced to a nondiabetic range of 4.0–6.0% using a DCCT-based assay.

Current NCEP/ATP III guidelines suggest that in patients with triglycerides ≥200 mg/dl, the “non-HDL cholesterol” (total cholesterol minus HDL) be utilized. The goal is ≤130 mg/dl (53).

For women, it has been suggested that the HDL goal be increased by 10 mg/dl.

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