Summary Table of Available Insulin and Associated Pregnancy Category (14–27)
| Insulin . | Time to Onset . | Peak Time . | Duration . | Pregnancy Category . |
|---|---|---|---|---|
| Regular U-100 | 30 min | 3 hours | 8 hours | B |
| Regular U-500 | 30 min | 3 hours | Up to 24 hours | B |
| Aspart | 10–15 min | 40–50 min | 3–5 hours | B |
| Lispro U-100 and U-200 | 10–15 min | 30–90 min | 3–5 hours | B |
| Glulisine | 10–15 min | 55 min | 3–5 hours | C |
| NPH | 1–2 hours | 4–8 hours | 10–20 hours | B |
| Detemir | 1–2 hours | None | 24 hours | B |
| Glargine U-100 | 1–2 hours | None | 24 hours | No human pregnancy data (previously C) |
| Glargine U-300 | >6 hours | None | 24 hours | No human pregnancy data |
| Degludec U-100 and U-200 | 1 hour | None | 42 hours (at steady state) | C |
| Inhaled human insulin | 12–15 min | 57 min | 2 hours | C |
| Insulin . | Time to Onset . | Peak Time . | Duration . | Pregnancy Category . |
|---|---|---|---|---|
| Regular U-100 | 30 min | 3 hours | 8 hours | B |
| Regular U-500 | 30 min | 3 hours | Up to 24 hours | B |
| Aspart | 10–15 min | 40–50 min | 3–5 hours | B |
| Lispro U-100 and U-200 | 10–15 min | 30–90 min | 3–5 hours | B |
| Glulisine | 10–15 min | 55 min | 3–5 hours | C |
| NPH | 1–2 hours | 4–8 hours | 10–20 hours | B |
| Detemir | 1–2 hours | None | 24 hours | B |
| Glargine U-100 | 1–2 hours | None | 24 hours | No human pregnancy data (previously C) |
| Glargine U-300 | >6 hours | None | 24 hours | No human pregnancy data |
| Degludec U-100 and U-200 | 1 hour | None | 42 hours (at steady state) | C |
| Inhaled human insulin | 12–15 min | 57 min | 2 hours | C |