Risk allele frequencies
| Marker SNP . | Gene region . | Alleles* . | Risk allele frequency . | . | . | . | . | Reference groups . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | . | . | Caucasian . | African American . | Hispanic . | Asian/Pacific Islander . | American Indian . | HapMap CEU . | HapMap YRI . | GWAS white cohorts . | ||||||
| n | 2,001 | 716 | 595 | 151 | 85 | |||||||||||
| rs1111875 | HHEX | C/T | 60.3 | 76.7 | 65.3 | 37.8 | 47.6 | 55.8 | 85.8 | 59.8† | ||||||
| rs7923837 | HHEX | G/A | 63.4 | 90.3 | 57.7 | 36.9 | 50.6 | 62.5 | 100 | 62.3† | ||||||
| rs11037909 | EXT2 | T/C | 72.9 | 84.5 | 54.6 | 55.1 | 22.2 | 70 | 84.2 | 72.9† | ||||||
| rs3740878 | EXT2 | T/C | 72.8 | 89.3 | 55.1 | 55.1 | 22.6 | 69.8 | 92.4 | 72.8† | ||||||
| rs1113132 | EXT2 | C/G | 73.1 | 90.0 | 44.7 | 44.9 | 77.4 | 70 | 92.5 | 73.3† | ||||||
| rs13266634 | SLC30A8 | C/T | 71.0 | 89.3 | 76.8 | 64.3 | 79.3 | 75.0 | 94.2 | 69.9† | ||||||
| rs7480010 | LOC387761 | G/A | 28.5 | 83.1 | 25.1 | 24.8 | 22.6 | 24.6 | 100 | 30.1† | ||||||
| rs10811661 | CDKN2A/B | T/C | 84.8 | 93.9 | 87.0 | 67.2 | 91.5 | 79.2 | 100 | 83‡ | ||||||
| rs1470579 | IGF2BP2 | C/A | 32.6 | 73.1 | 30.7 | 31.9 | 24.1 | 29.2 | 86.7 | 30‡ | ||||||
| rs7754840 | CDKAL1 | C/G | 32.7 | 56.8 | 32.5 | 39.8 | 30.5 | 30.8 | 66.7 | 31‡ | ||||||
| Marker SNP . | Gene region . | Alleles* . | Risk allele frequency . | . | . | . | . | Reference groups . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | . | . | Caucasian . | African American . | Hispanic . | Asian/Pacific Islander . | American Indian . | HapMap CEU . | HapMap YRI . | GWAS white cohorts . | ||||||
| n | 2,001 | 716 | 595 | 151 | 85 | |||||||||||
| rs1111875 | HHEX | C/T | 60.3 | 76.7 | 65.3 | 37.8 | 47.6 | 55.8 | 85.8 | 59.8† | ||||||
| rs7923837 | HHEX | G/A | 63.4 | 90.3 | 57.7 | 36.9 | 50.6 | 62.5 | 100 | 62.3† | ||||||
| rs11037909 | EXT2 | T/C | 72.9 | 84.5 | 54.6 | 55.1 | 22.2 | 70 | 84.2 | 72.9† | ||||||
| rs3740878 | EXT2 | T/C | 72.8 | 89.3 | 55.1 | 55.1 | 22.6 | 69.8 | 92.4 | 72.8† | ||||||
| rs1113132 | EXT2 | C/G | 73.1 | 90.0 | 44.7 | 44.9 | 77.4 | 70 | 92.5 | 73.3† | ||||||
| rs13266634 | SLC30A8 | C/T | 71.0 | 89.3 | 76.8 | 64.3 | 79.3 | 75.0 | 94.2 | 69.9† | ||||||
| rs7480010 | LOC387761 | G/A | 28.5 | 83.1 | 25.1 | 24.8 | 22.6 | 24.6 | 100 | 30.1† | ||||||
| rs10811661 | CDKN2A/B | T/C | 84.8 | 93.9 | 87.0 | 67.2 | 91.5 | 79.2 | 100 | 83‡ | ||||||
| rs1470579 | IGF2BP2 | C/A | 32.6 | 73.1 | 30.7 | 31.9 | 24.1 | 29.2 | 86.7 | 30‡ | ||||||
| rs7754840 | CDKAL1 | C/G | 32.7 | 56.8 | 32.5 | 39.8 | 30.5 | 30.8 | 66.7 | 31‡ | ||||||
Data are percent.
Putative risk allele listed first.
French, 3.
Scandinavian, 7. CEU, European ancestry. YRI, African ancestry.