Skip to Main Content
TABLE 1

Echocardiographic evaluation of contractile function in wild-type and Akita mice at 20, 36, and 54 weeks of age

nFractional shortening (%)Ejection fraction (%)Heart rate (bpm)Stroke volume (μl/g body wt)Cardiac output (μl · min−1 · g−1 body wt)
Wild type (20 weeks) 38.6 ± 2.4 76 ± 3 415 ± 12 1.13 ± 0.03 467 ± 14 
Akita (20 weeks) 38.7 ± 2.4 76 ± 3 472 ± 31 1.12 ± 0.07 527 ± 15* 
Wild type (36 weeks) 39.6 ± 1.2 78 ± 1 470 ± 41 0.97 ± 0.04 456 ± 25 
Akita (36 weeks) 39.7 ± 2.7 78 ± 3 421 ± 29 1.13 ± 0.04* 476 ± 33 
Wild type (54 weeks) 24.6 ± 1.9 57 ± 3 523 ± 29 1.00 ± 0.10 524 ± 28 
Akita (54 weeks) 27.6 ± 1.9 62 ± 3 448 ± 28 0.95 ± 0.04 426 ± 28* 
nFractional shortening (%)Ejection fraction (%)Heart rate (bpm)Stroke volume (μl/g body wt)Cardiac output (μl · min−1 · g−1 body wt)
Wild type (20 weeks) 38.6 ± 2.4 76 ± 3 415 ± 12 1.13 ± 0.03 467 ± 14 
Akita (20 weeks) 38.7 ± 2.4 76 ± 3 472 ± 31 1.12 ± 0.07 527 ± 15* 
Wild type (36 weeks) 39.6 ± 1.2 78 ± 1 470 ± 41 0.97 ± 0.04 456 ± 25 
Akita (36 weeks) 39.7 ± 2.7 78 ± 3 421 ± 29 1.13 ± 0.04* 476 ± 33 
Wild type (54 weeks) 24.6 ± 1.9 57 ± 3 523 ± 29 1.00 ± 0.10 524 ± 28 
Akita (54 weeks) 27.6 ± 1.9 62 ± 3 448 ± 28 0.95 ± 0.04 426 ± 28* 

Data are means ± SE unless otherwise indicated.

*

P < 0.05 vs. wild type.

Close Modal

or Create an Account

Close Modal
Close Modal