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TABLE 1

Anthropometric and metabolic characteristics of the study groups

Normal glucose tolerant
Type 2 diabetes
MenWomenMenWomen
n 12 18 48 76 
Age (years) 61 ± 12 56 ± 15 62 ± 7 62 ± 8 
Body weight (kg) 91 ± 20* 89 ± 23 103 ± 17 90 ± 17 
BMI (kg/m229 ± 3* 33 ± 4 35 ± 6* 33 ± 7 
Body fat (%) 22 ± 1* 41 ± 8 30 ± 5 41 ± 6 
A1C (%) 5.5 ± 1.8* 5.4 ± 0.7* 6.6 ± 1.0 6.6 ± 1.0 
Fasting plasma glucose (mmol/l) 5.3 ± 1.2* 5.2 ± 0.6* 7.5 ± 2.2 7.2 ± 2.0 
Fasting plasma insulin (pmol/l) 38 ± 12* 58 ± 11* 136 ± 253 145 ± 116 
Free fatty acids (mmol/l) 0.45 ± 0.48* 0.48 ± 0.27* 0.66 ± 0.25 0.62 ± 0.26 
Cholesterol (mmol/l) 4.3 ± 0.6* 5.2 ± 0.8 5.0 ± 1.0 5.5 ± 1.1 
HDL cholesterol (mmol/l) 1.3 ± 0.2* 1.6 ± 0.2* 1.1 ± 0.2 1.4 ± 0.3 
LDL cholesterol (mmol/l) 2.7 ± 0.6* 3.4 ± 0.3* 3.3 ± 1.0 3.7 ± 0.9 
Triglycerides (mmol/l) 1.4 ± 0.6* 1.5 ± 0.8* 2.0 ± 0.7 2.0 ± 1.2 
Leptin 9.7 ± 7.7* 25.3 ± 16.9 14.8 ± 11.0 28.8 ± 18.9 
Adiponectin 5.5 ± 2.3* 8.6 ± 3.8 3.7 ± 2.4 6.5 ± 3.2 
hsCRP (mg/dl) 0.22 ± 0.1* 0.29 ± 0.1* 0.34 ± 0.27 0.45 ± 0.36 
Normal glucose tolerant
Type 2 diabetes
MenWomenMenWomen
n 12 18 48 76 
Age (years) 61 ± 12 56 ± 15 62 ± 7 62 ± 8 
Body weight (kg) 91 ± 20* 89 ± 23 103 ± 17 90 ± 17 
BMI (kg/m229 ± 3* 33 ± 4 35 ± 6* 33 ± 7 
Body fat (%) 22 ± 1* 41 ± 8 30 ± 5 41 ± 6 
A1C (%) 5.5 ± 1.8* 5.4 ± 0.7* 6.6 ± 1.0 6.6 ± 1.0 
Fasting plasma glucose (mmol/l) 5.3 ± 1.2* 5.2 ± 0.6* 7.5 ± 2.2 7.2 ± 2.0 
Fasting plasma insulin (pmol/l) 38 ± 12* 58 ± 11* 136 ± 253 145 ± 116 
Free fatty acids (mmol/l) 0.45 ± 0.48* 0.48 ± 0.27* 0.66 ± 0.25 0.62 ± 0.26 
Cholesterol (mmol/l) 4.3 ± 0.6* 5.2 ± 0.8 5.0 ± 1.0 5.5 ± 1.1 
HDL cholesterol (mmol/l) 1.3 ± 0.2* 1.6 ± 0.2* 1.1 ± 0.2 1.4 ± 0.3 
LDL cholesterol (mmol/l) 2.7 ± 0.6* 3.4 ± 0.3* 3.3 ± 1.0 3.7 ± 0.9 
Triglycerides (mmol/l) 1.4 ± 0.6* 1.5 ± 0.8* 2.0 ± 0.7 2.0 ± 1.2 
Leptin 9.7 ± 7.7* 25.3 ± 16.9 14.8 ± 11.0 28.8 ± 18.9 
Adiponectin 5.5 ± 2.3* 8.6 ± 3.8 3.7 ± 2.4 6.5 ± 3.2 
hsCRP (mg/dl) 0.22 ± 0.1* 0.29 ± 0.1* 0.34 ± 0.27 0.45 ± 0.36 

Data are means ± SD.

*

P < 0.05 for patients with type 2 diabetes versus normal glucose tolerant individuals within each sex.

P < 0.05 for difference between men and women within the normal glucose tolerant or type 2 diabetes group.

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