Association between baseline lipid factors (PCA extracted) and T2D risk (adjusted for age, sex, and intervention group)
. | Quartiles of factors . | Linear trend . | Per SD increase . | |||
---|---|---|---|---|---|---|
Q1 . | Q2 . | Q3 . | Q4 . | |||
Factor 3* | Ref | 0.62 (0.37–1.05) | 0.79 (0.47–1.32) | 0.45 (0.26–0.79) | 0.003 | 0.70 (0.57–0.85) |
Factor 7* | Ref | 0.62 (0.39–0.97) | 0.39 (0.23–0.67) | 0.36 (0.20–0.63) | <0.001 | 0.58 (0.49–0.70) |
Factor 10* | Ref | 0.80 (0.48–1.33) | 0.48 (0.28–0.81) | 0.56 (0.33–0.95) | 0.012 | 0.74 (0.62–0.88) |
Factor 13* | Ref | 1.00 (0.61–1.66) | 0.78 (0.47–1.32) | 0.58 (0.34–1.00) | 0.166 | 0.93 (0.78–1.10) |
Factor 1* | Ref | 1.39 (0.77–2.52) | 2.24 (1.29–3.88) | 2.72 (1.59–4.66) | <0.001 | 1.62 (1.36–1.92) |
Factor 5* | Ref | 1.44 (0.83–2.45) | 1.14 (0.65–2.00) | 2.22 (1.31–3.77) | 0.022 | 1.24 (1.04–1.47) |
Factor 11* | Ref | 1.25 (0.72–2.18) | 1.78 (1.03–3.10) | 2.02 (1.15–3.54) | 0.009 | 1.18 (0.99–1.40) |
. | Quartiles of factors . | Linear trend . | Per SD increase . | |||
---|---|---|---|---|---|---|
Q1 . | Q2 . | Q3 . | Q4 . | |||
Factor 3* | Ref | 0.62 (0.37–1.05) | 0.79 (0.47–1.32) | 0.45 (0.26–0.79) | 0.003 | 0.70 (0.57–0.85) |
Factor 7* | Ref | 0.62 (0.39–0.97) | 0.39 (0.23–0.67) | 0.36 (0.20–0.63) | <0.001 | 0.58 (0.49–0.70) |
Factor 10* | Ref | 0.80 (0.48–1.33) | 0.48 (0.28–0.81) | 0.56 (0.33–0.95) | 0.012 | 0.74 (0.62–0.88) |
Factor 13* | Ref | 1.00 (0.61–1.66) | 0.78 (0.47–1.32) | 0.58 (0.34–1.00) | 0.166 | 0.93 (0.78–1.10) |
Factor 1* | Ref | 1.39 (0.77–2.52) | 2.24 (1.29–3.88) | 2.72 (1.59–4.66) | <0.001 | 1.62 (1.36–1.92) |
Factor 5* | Ref | 1.44 (0.83–2.45) | 1.14 (0.65–2.00) | 2.22 (1.31–3.77) | 0.022 | 1.24 (1.04–1.47) |
Factor 11* | Ref | 1.25 (0.72–2.18) | 1.78 (1.03–3.10) | 2.02 (1.15–3.54) | 0.009 | 1.18 (0.99–1.40) |
Data are HR (95% CI) unless otherwise indicated. Boldface type indicates P values <0.05 for the association with T2D (HR). Ref, reference; Q, quartile.
*Additionally adjusted for the rest of the factors (1–15).