Table 3

HR and 95% CI of avascular necrosis of the femoral head associated with diabetes and comorbidities

Crude
Adjusted
VariableHR95% CIHR95% CI
Sex (male vs. female) 1.31 1.12–1.55 1.30 1.25–1.35 
Age (every 1 year) 1.01 1.004–1.02 1.01 1.003–1.01 
Diabetes (yes vs. no) 1.37 1.14–1.65 1.16 1.11–1.21 
Baseline comorbidities (yes vs. no)     
 Alcohol-related disease 4.54 3.46–5.94 3.80 3.56–4.05 
 Cardiovascular disease 1.53 1.28–1.81 1.11 1.06–1.17 
 Chronic kidney disease 1.67 1.18–2.37 1.24 1.14–1.35 
 Chronic obstructive pulmonary disease 1.58 1.30–1.92 1.18 1.13–1.24 
 Hyperlipidemia 1.39 1.17–1.66 1.11 1.06–1.16 
 Hypertension 1.49 1.27–1.75 1.17 1.12–1.22 
 Hip fracture 4.96 3.02–8.15 4.21 3.75–4.73 
 Thalassemia 2.35 0.76–7.29 2.08 1.60–2.70 
 Oral corticosteroid use 1.50 1.25–1.80 1.34 1.28–1.39 
Crude
Adjusted
VariableHR95% CIHR95% CI
Sex (male vs. female) 1.31 1.12–1.55 1.30 1.25–1.35 
Age (every 1 year) 1.01 1.004–1.02 1.01 1.003–1.01 
Diabetes (yes vs. no) 1.37 1.14–1.65 1.16 1.11–1.21 
Baseline comorbidities (yes vs. no)     
 Alcohol-related disease 4.54 3.46–5.94 3.80 3.56–4.05 
 Cardiovascular disease 1.53 1.28–1.81 1.11 1.06–1.17 
 Chronic kidney disease 1.67 1.18–2.37 1.24 1.14–1.35 
 Chronic obstructive pulmonary disease 1.58 1.30–1.92 1.18 1.13–1.24 
 Hyperlipidemia 1.39 1.17–1.66 1.11 1.06–1.16 
 Hypertension 1.49 1.27–1.75 1.17 1.12–1.22 
 Hip fracture 4.96 3.02–8.15 4.21 3.75–4.73 
 Thalassemia 2.35 0.76–7.29 2.08 1.60–2.70 
 Oral corticosteroid use 1.50 1.25–1.80 1.34 1.28–1.39 

†Adjusting for sex, age, alcohol-related disease, cardiovascular disease, chronic kidney disease, chronic obstructive pulmonary disease, hyperlipidemia, hypertension, hip fracture, thalassemia, and oral corticosteroid use.

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