Table 2

Primary outcomes (weight change and HbA1c change) for participants who have finished the program, including respectively those for whom all data fields, except HbA1c, were complete (N = 26,753) and for those with all data fields complete (N = 16,083): univariate analysis

Mean weight change (kg), intention-to-treatMean HbA1c change (mmol/mol), intention-to-treat
nBaselineChange95% CIP valuenBaselineChange95% CIP value
Total 26,753 83.4 −2.3 −2.3, −2.2 NA 16,083 41.8 −1.3 −1.3, −1.2 NA 
Sex           
 Male 11,942 90 −2.5 −2.6, −2.5 <0.001 7,065 41.7 −1.4 −1.4, −1.3 <0.001 
 Female 14,800 78.1 −2.0 −2.1, −2.0  9,010 41.8 −1.2 −1.2, −1.1  
 Indeterminate 11 84.7 −2.8 −5.1, −0.5  8 42.1 −0.1 −2.9, 2.7  
Age band (years)           
 <40 604 90.3 −1.0 −1.3, −0.8 <0.001 342 41.1 −0.7 −1.0, −0.3 <0.001 
 40–44 693 90.6 −1.0 −1.3, −0.8  388 41.5 −0.7 −1.0, −0.5  
 45–49 1,116 90.4 −1.6 −1.8, −1.4  629 41.5 −0.6 −0.8, −0.4  
 50–54 1,873 88.8 −1.7 −1.9, −1.5  1,082 41.9 −1.0 −1.2, −0.9  
 55–59 2,723 87.8 −2.1 −2.2, −1.9  1,599 41.7 −1.1 −1.2, −0.9  
 60–64 3,489 85.2 −2.4 −2.5, −2.3  2,161 41.7 −1.2 −1.4, −1.1  
 65–69 5,201 83.8 −2.6 −2.7, −2.4  3,216 41.7 −1.4 −1.6, −1.3  
 70–74 5,161 81.6 −2.6 −2.7, −2.5  3,167 41.8 −1.5 −1.6, −1.4  
 ≥75 5,893 77.2 −2.2 −2.3, −2.1  3,499 42 −1.3 −1.4, −1.1  
Ethnicity           
 Asian 3,087 74.8 −1.0 −1.1, −0.9 <0.001 1,844 42.1 −0.9 −1.0, −0.8 <0.001 
 Black 1,821 86.3 −1.7 −1.9, −1.6  1,167 42.2 −0.8 −1.0, −0.6  
 Mixed 513 84.1 −1.7 −2.0, −1.4  285 42.2 −1.0 −1.3, −0.7  
 Other 181 80.9 −1.5 −2.0, −1.1  95 41.3 −0.6 −1.1, −0.0  
 White 21,151 84.5 −2.5 −2.5, −2.4  12,692 41.7 −1.4 −1.4, −1.3  
Deprivation           
 IMD 1 (most deprived) 4,430 84.8 −1.8 −1.9, −1.6 <0.001 2,631 41.9 −0.9 −1.0, −0.7 <0.001 
 IMD 2 5,161 84 −2.1 −2.2, −2.0  3,287 41.7 −1.2 −1.3, −1.1  
 IMD 3 5,922 83.1 −2.2 −2.3, −2.1  3,741 41.9 −1.3 −1.4, −1.2  
 IMD 4 5,635 83.2 −2.5 −2.6, −2.4  3,268 41.7 −1.3 −1.4, −1.2  
 IMD 5 (least deprived) 5,605 82.4 −2.6 −2.7, −2.5  3,156 41.8 −1.5 −1.7, −1.4  
BMI group           
 Underweight/healthy 4,205 62.7 −1.4 −1.5, −1.3 <0.001 2,630 41.3 −1.4 −1.5, −1.3 0.001 
 Overweight 9,865 76.5 −2.2 −2.3, −2.1  6,033 41.6 −1.3 −1.4, −1.2  
 Obese 12,683 95.7 −2.6 −2.6, −2.5  7,420 42.1 −1.2 −1.2, −1.1  
Provider           
 Ingeus UK 5,868 84.9 −2.1 −2.2, −2.0 <0.001 35 39.7 −1.0 −2.4, 0.4 <0.001 
 Living Well Taking Control 3,067 84.2 −1.9 −2.1, −1.8  2,066 40.9 −0.5 −0.6, −0.4  
 ICS Health & Wellbeing 11,752 82.4 −2.3 −2.3, −2.2  8,890 42.3 −1.3 −1.4, −1.2  
 Reed Momenta 6,066 83.7 −2.6 −2.7, −2.4  5,092 41.2 −1.5 −1.6, −1.4  
Mean weight change (kg), intention-to-treatMean HbA1c change (mmol/mol), intention-to-treat
nBaselineChange95% CIP valuenBaselineChange95% CIP value
Total 26,753 83.4 −2.3 −2.3, −2.2 NA 16,083 41.8 −1.3 −1.3, −1.2 NA 
Sex           
 Male 11,942 90 −2.5 −2.6, −2.5 <0.001 7,065 41.7 −1.4 −1.4, −1.3 <0.001 
 Female 14,800 78.1 −2.0 −2.1, −2.0  9,010 41.8 −1.2 −1.2, −1.1  
 Indeterminate 11 84.7 −2.8 −5.1, −0.5  8 42.1 −0.1 −2.9, 2.7  
Age band (years)           
 <40 604 90.3 −1.0 −1.3, −0.8 <0.001 342 41.1 −0.7 −1.0, −0.3 <0.001 
 40–44 693 90.6 −1.0 −1.3, −0.8  388 41.5 −0.7 −1.0, −0.5  
 45–49 1,116 90.4 −1.6 −1.8, −1.4  629 41.5 −0.6 −0.8, −0.4  
 50–54 1,873 88.8 −1.7 −1.9, −1.5  1,082 41.9 −1.0 −1.2, −0.9  
 55–59 2,723 87.8 −2.1 −2.2, −1.9  1,599 41.7 −1.1 −1.2, −0.9  
 60–64 3,489 85.2 −2.4 −2.5, −2.3  2,161 41.7 −1.2 −1.4, −1.1  
 65–69 5,201 83.8 −2.6 −2.7, −2.4  3,216 41.7 −1.4 −1.6, −1.3  
 70–74 5,161 81.6 −2.6 −2.7, −2.5  3,167 41.8 −1.5 −1.6, −1.4  
 ≥75 5,893 77.2 −2.2 −2.3, −2.1  3,499 42 −1.3 −1.4, −1.1  
Ethnicity           
 Asian 3,087 74.8 −1.0 −1.1, −0.9 <0.001 1,844 42.1 −0.9 −1.0, −0.8 <0.001 
 Black 1,821 86.3 −1.7 −1.9, −1.6  1,167 42.2 −0.8 −1.0, −0.6  
 Mixed 513 84.1 −1.7 −2.0, −1.4  285 42.2 −1.0 −1.3, −0.7  
 Other 181 80.9 −1.5 −2.0, −1.1  95 41.3 −0.6 −1.1, −0.0  
 White 21,151 84.5 −2.5 −2.5, −2.4  12,692 41.7 −1.4 −1.4, −1.3  
Deprivation           
 IMD 1 (most deprived) 4,430 84.8 −1.8 −1.9, −1.6 <0.001 2,631 41.9 −0.9 −1.0, −0.7 <0.001 
 IMD 2 5,161 84 −2.1 −2.2, −2.0  3,287 41.7 −1.2 −1.3, −1.1  
 IMD 3 5,922 83.1 −2.2 −2.3, −2.1  3,741 41.9 −1.3 −1.4, −1.2  
 IMD 4 5,635 83.2 −2.5 −2.6, −2.4  3,268 41.7 −1.3 −1.4, −1.2  
 IMD 5 (least deprived) 5,605 82.4 −2.6 −2.7, −2.5  3,156 41.8 −1.5 −1.7, −1.4  
BMI group           
 Underweight/healthy 4,205 62.7 −1.4 −1.5, −1.3 <0.001 2,630 41.3 −1.4 −1.5, −1.3 0.001 
 Overweight 9,865 76.5 −2.2 −2.3, −2.1  6,033 41.6 −1.3 −1.4, −1.2  
 Obese 12,683 95.7 −2.6 −2.6, −2.5  7,420 42.1 −1.2 −1.2, −1.1  
Provider           
 Ingeus UK 5,868 84.9 −2.1 −2.2, −2.0 <0.001 35 39.7 −1.0 −2.4, 0.4 <0.001 
 Living Well Taking Control 3,067 84.2 −1.9 −2.1, −1.8  2,066 40.9 −0.5 −0.6, −0.4  
 ICS Health & Wellbeing 11,752 82.4 −2.3 −2.3, −2.2  8,890 42.3 −1.3 −1.4, −1.2  
 Reed Momenta 6,066 83.7 −2.6 −2.7, −2.4  5,092 41.2 −1.5 −1.6, −1.4  

IMD, Index of Multiple Deprivation; NA, not available.

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