American Diabetes Association

Table 2

Performance of prescriptive algorithms

			kNN		LASSO		Random forest
All patient visits (N = 48,140)
Mean HbA_1c benefit relative to standard of care (SE)
Percent			−0.14 (0.01)*		−0.13 (0.01)*		−0.07 (0.01)*
mmol/mol			−1.5 (0.1)*		−1.4 (0.1)*		−0.8 (0.1)*
Visits for which algorithm’s recommendation differed from observed standard of care
Number of visits (%)			15,323 (31.8)		12,684 (26.3)		14,302 (29.7)
Mean HbA_1c benefit relative to standard of care (SE)
Percent			−0.44 (0.03)*		−0.45 (0.03)*		−0.26 (0.03)*
mmol/mol			−4.8 (0.3)*		−4.9 (0.3)*		−2.8 (0.3)*

			kNN		LASSO		Random forest
All patient visits (N = 48,140)
Mean HbA_1c benefit relative to standard of care (SE)
Percent			−0.14 (0.01)*		−0.13 (0.01)*		−0.07 (0.01)*
mmol/mol			−1.5 (0.1)*		−1.4 (0.1)*		−0.8 (0.1)*
Visits for which algorithm’s recommendation differed from observed standard of care
Number of visits (%)			15,323 (31.8)		12,684 (26.3)		14,302 (29.7)
Mean HbA_1c benefit relative to standard of care (SE)
Percent			−0.44 (0.03)*		−0.45 (0.03)*		−0.26 (0.03)*
mmol/mol			−4.8 (0.3)*		−4.9 (0.3)*		−2.8 (0.3)*

*P < 0.001.