Table 6.3

Classification of hypoglycemia*

LevelGlycemic criteriaDescription
Hypoglycemia alert value (level 1) ≤70 mg/dL (3.9 mmol/L) Sufficiently low for treatment with fast-acting carbohydrate and dose adjustment of glucose-lowering therapy 
Clinically significant hypoglycemia (level 2) <54 mg/dL (3.0 mmol/L) Sufficiently low to indicate serious, clinically important hypoglycemia 
Severe hypoglycemia (level 3) No specific glucose threshold Hypoglycemia associated with severe cognitive impairment requiring external assistance for recovery 
LevelGlycemic criteriaDescription
Hypoglycemia alert value (level 1) ≤70 mg/dL (3.9 mmol/L) Sufficiently low for treatment with fast-acting carbohydrate and dose adjustment of glucose-lowering therapy 
Clinically significant hypoglycemia (level 2) <54 mg/dL (3.0 mmol/L) Sufficiently low to indicate serious, clinically important hypoglycemia 
Severe hypoglycemia (level 3) No specific glucose threshold Hypoglycemia associated with severe cognitive impairment requiring external assistance for recovery 

*Adapted from ref. 75.

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