Median cost of insulin products in the U.S. calculated as AWP (44) and NADAC (45) per 1,000 units of specified dosage form/product
| Insulins . | Compounds . | Dosage form/product . | Median AWP (min, max)* . | Median NADAC (min, max)* . |
|---|---|---|---|---|
| Rapid-acting analogs | • Lispro biosimilar | U-100 vial | $280 | $226 |
| U-100 prefilled pen | $361 | $289 | ||
| • Glulisine | U-100 vial | $324 | $260 | |
| U-100 prefilled pen | $417 | $334 | ||
| • Lispro | U-100 vial | $330 | $264 | |
| U-100 3 mL cartridges | $408 | $326 | ||
| U-100 prefilled pen; U-200 prefilled pen | $424 | $340 | ||
| • Aspart | U-100 vial | $347 | $278 | |
| U-100 3 mL cartridges | $430 | $343 | ||
| U-100 prefilled pen | $447 | $358 | ||
| • Inhaled insulin | Inhalation cartridges | $993 | $606 | |
| Short-acting | • Human Regular | U-100 vial | $165 ($165, $178) | $135 ($135, $146) |
| Intermediate-acting | • Human NPH | U-100 vial | $165 ($165, $178) | $135 ($135, $144) |
| U-100 prefilled pen | $377 | $304 | ||
| Concentrated Human Regular insulin | • U-500 Human Regular insulin | U-500 vial | $178 | $142 |
| U-500 prefilled pen | $230 | $184 | ||
| Basal analogs | • Glargine biosimilar | U-100 prefilled pen | $261 | $209 |
| • Glargine | U-100 vial; U-100 prefilled pen | $323 | $259 | |
| U-300 prefilled pen | $331 | $266 | ||
| • Detemir | U-100 vial; U-100 prefilled pen | $353 | $281 | |
| • Degludec | U-100 prefilled pen; U-200 prefilled pen | $388 | $310 | |
| Premixed insulin products | • NPH/Regular 70/30 | U-100 vial | $165 ($165, $178) | $135 ($135, $144) |
| U-100 prefilled pen | $377 | $306 | ||
| • Lispro 50/50 | U-100 vial | $342 | $274 | |
| U-100 prefilled pen | $424 | $340 | ||
| • Lispro 75/25 | U-100 vial | $342 | $273 | |
| U-100 prefilled pen | $424 | $340 | ||
| • Aspart 70/30 | U-100 vial | $360 | $288 | |
| U-100 prefilled pen | $447 | $358 | ||
| Premixed insulin/GLP-1 receptor agonist products | • Degludec/Liraglutide | 100/3.6 prefilled pen | $793 | $638 |
| • Glargine/Lixisenatide | 100/33 prefilled pen | $537 | $431 |
| Insulins . | Compounds . | Dosage form/product . | Median AWP (min, max)* . | Median NADAC (min, max)* . |
|---|---|---|---|---|
| Rapid-acting analogs | • Lispro biosimilar | U-100 vial | $280 | $226 |
| U-100 prefilled pen | $361 | $289 | ||
| • Glulisine | U-100 vial | $324 | $260 | |
| U-100 prefilled pen | $417 | $334 | ||
| • Lispro | U-100 vial | $330 | $264 | |
| U-100 3 mL cartridges | $408 | $326 | ||
| U-100 prefilled pen; U-200 prefilled pen | $424 | $340 | ||
| • Aspart | U-100 vial | $347 | $278 | |
| U-100 3 mL cartridges | $430 | $343 | ||
| U-100 prefilled pen | $447 | $358 | ||
| • Inhaled insulin | Inhalation cartridges | $993 | $606 | |
| Short-acting | • Human Regular | U-100 vial | $165 ($165, $178) | $135 ($135, $146) |
| Intermediate-acting | • Human NPH | U-100 vial | $165 ($165, $178) | $135 ($135, $144) |
| U-100 prefilled pen | $377 | $304 | ||
| Concentrated Human Regular insulin | • U-500 Human Regular insulin | U-500 vial | $178 | $142 |
| U-500 prefilled pen | $230 | $184 | ||
| Basal analogs | • Glargine biosimilar | U-100 prefilled pen | $261 | $209 |
| • Glargine | U-100 vial; U-100 prefilled pen | $323 | $259 | |
| U-300 prefilled pen | $331 | $266 | ||
| • Detemir | U-100 vial; U-100 prefilled pen | $353 | $281 | |
| • Degludec | U-100 prefilled pen; U-200 prefilled pen | $388 | $310 | |
| Premixed insulin products | • NPH/Regular 70/30 | U-100 vial | $165 ($165, $178) | $135 ($135, $144) |
| U-100 prefilled pen | $377 | $306 | ||
| • Lispro 50/50 | U-100 vial | $342 | $274 | |
| U-100 prefilled pen | $424 | $340 | ||
| • Lispro 75/25 | U-100 vial | $342 | $273 | |
| U-100 prefilled pen | $424 | $340 | ||
| • Aspart 70/30 | U-100 vial | $360 | $288 | |
| U-100 prefilled pen | $447 | $358 | ||
| Premixed insulin/GLP-1 receptor agonist products | • Degludec/Liraglutide | 100/3.6 prefilled pen | $793 | $638 |
| • Glargine/Lixisenatide | 100/33 prefilled pen | $537 | $431 |
AWP, average wholesale price; GLP-1, glucagon-like peptide 1; NADAC, National Average Drug Acquisition Cost.
AWP or NADAC calculated as in Table 9.2; median listed alone when only one product and/or price.