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Table 1—

Results of tests of information processing during euglycemia and hyperglycemia in 20 adults with type 2 diabetes

SubtestEuglycemiaHyperglycemiaPFEta2AgeSexGIRHbA1cTAEAHT
Digit Symbol Substitution test 70.2 ± 8.4 66.8 ± 7.8 0.03 5.64 0.24 0.38 0.26 0.65 0.71 0.64 0.57 0.96 
Trail Making B test 40.9 ± 7.8 43.9 ± 8.0 0.04 4.77 0.23 0.74 0.77 0.34 0.32 0.38 0.39 0.39 
Simple Reaction Time test             
    Mean 359.9 ± 84.6 373.7 ± 72.3 0.10 2.99 0.14 0.81 0.43 0.76 0.33 0.41 0.28 0.08 
    SD 73.3 ± 11.2 77.5 ± 17.6 0.10 0.47 0.15 0.96 0.18 0.98 0.81 0.50 0.45 0.68 
    Coefficient of variation 21.09 ± 6.86 21.82 ± 6.01 0.38 0.82 0.01 0.92 0.19 0.82 0.65 0.31 0.09 0.16 
Four-Choice Reaction Time test             
    Mean 710.0 ± 116.7 775.7 ± 122.9 <0.0001 23.05 0.56 0.55 0.12 0.48 0.92 0.46 0.76 0.74 
    SD 133.1 ± 23.6 139.5 ± 41.2 0.09 0.68 0.18 0.09 0.48 0.60 0.70 0.67 0.34 0.26 
    Coefficient of variation 18.73 ± 2.77 18.22 ± 4.02 0.64 0.23 0.01 0.06 0.76 0.61 0.68 0.80 0.41 0.95 
    Number of errors 0.5 ± 0.1 0.4 ± 0.1 0.43 0.54 0.09 0.54 0.65 0.36 0.62 0.51 0.22 0.31 
SubtestEuglycemiaHyperglycemiaPFEta2AgeSexGIRHbA1cTAEAHT
Digit Symbol Substitution test 70.2 ± 8.4 66.8 ± 7.8 0.03 5.64 0.24 0.38 0.26 0.65 0.71 0.64 0.57 0.96 
Trail Making B test 40.9 ± 7.8 43.9 ± 8.0 0.04 4.77 0.23 0.74 0.77 0.34 0.32 0.38 0.39 0.39 
Simple Reaction Time test             
    Mean 359.9 ± 84.6 373.7 ± 72.3 0.10 2.99 0.14 0.81 0.43 0.76 0.33 0.41 0.28 0.08 
    SD 73.3 ± 11.2 77.5 ± 17.6 0.10 0.47 0.15 0.96 0.18 0.98 0.81 0.50 0.45 0.68 
    Coefficient of variation 21.09 ± 6.86 21.82 ± 6.01 0.38 0.82 0.01 0.92 0.19 0.82 0.65 0.31 0.09 0.16 
Four-Choice Reaction Time test             
    Mean 710.0 ± 116.7 775.7 ± 122.9 <0.0001 23.05 0.56 0.55 0.12 0.48 0.92 0.46 0.76 0.74 
    SD 133.1 ± 23.6 139.5 ± 41.2 0.09 0.68 0.18 0.09 0.48 0.60 0.70 0.67 0.34 0.26 
    Coefficient of variation 18.73 ± 2.77 18.22 ± 4.02 0.64 0.23 0.01 0.06 0.76 0.61 0.68 0.80 0.41 0.95 
    Number of errors 0.5 ± 0.1 0.4 ± 0.1 0.43 0.54 0.09 0.54 0.65 0.36 0.62 0.51 0.22 0.31 

Data are means ±SD. The effects of age, sex, glucose infusion rate (GIR), HbA1c, and mood as covariates are also shown (all P values). EA, energetic arousal; HT, hedonic tone;TA, tense arousal.

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