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Table 3—

Characteristics of subjects who met ATP III criteria, insulin-resistant subjects who did not meet ATP III criteria, and insulin-sensitive subjects

VariablesATP III+ATP III
Insulin resistantInsulin sensitive
n 20 45 
Age (years) 45.6 ± 7.8 37.2 ± 11.0 33.0 ± 10.9 
BMI (kg/m233.6 ± 3.1* 28.2 ± 4.5 24.9 ± 3.5* 
Waist circumference (cm) 104.2 ± 11.0* 93.8 ± 9.3 82.8 ± 9.0* 
Abdominal obesity (%) 89.9* 30.0 13.3 
Systolic blood pressure (mmHg) 123.4 ± 14.1 117.2 ± 10.5 114.8 ± 11.8 
Diastolic blood pressure (mmHg) 72.4 ± 10.5 66.5 ± 8.7 64.2 ± 9.5 
Abnormal blood pressure, (%) 55.6* 10.0 13.3 
Triglycerides (mg/dl) 220.7 ± 88.6* 125.6 ± 55.0 84.6 ± 29.5* 
Abnormal triglycerides (%) 77.8* 25.0 4.4* 
HDL (mg/dl) 34.4 ± 5.7 38.5 ± 11.2 42.8 ± 11.0 
Abnormal HDL (%) 100.0 70.0 68.9 
Fasting glucose (mg/dl) 90.7 ± 5.5 91.7 ± 8.2 84.0 ± 7.0* 
Impaired glucose tolerance (%) 25.0 20.0 13.3 
Glucose disposal rate (mg · kg−1 · min−111.1 ± 3.8 10.6 ± 1.4 15.6 ± 2.2* 
NMR profile (selected)    
 Large VLDL concentration (nmol/l) 6.5 ± 4.1 3.9 ± 4.1 1.4 ± 1.8* 
 VLDL size (nm) 56.7 ± 8.1 54.4 ± 10.1 48.2 ± 8.7* 
 Total LDL concentration (nmol/l) 1,696 ± 469 1,431 ± 424 1,155 ± 287* 
 Large LDL concentration (nmol/l) 353 ± 283 479 ± 379 620 ± 321 
 Small to intermediate LDL (nmol/l) 1,332 ± 489 938 ± 533 523 ± 280* 
 LDL size (nm) 20.4 ± 0.6 20.6 ± 0.7 21.2 ± 0.5* 
 Large HDL concentration (μmol/l) 2.3 ± 1.8 4.3 ± 3.3 7.1 ± 3.3* 
 HDL size (nm) 8.5 ± 0.2 8.6 ± 0.3 9.0 ± 0.4* 
VariablesATP III+ATP III
Insulin resistantInsulin sensitive
n 20 45 
Age (years) 45.6 ± 7.8 37.2 ± 11.0 33.0 ± 10.9 
BMI (kg/m233.6 ± 3.1* 28.2 ± 4.5 24.9 ± 3.5* 
Waist circumference (cm) 104.2 ± 11.0* 93.8 ± 9.3 82.8 ± 9.0* 
Abdominal obesity (%) 89.9* 30.0 13.3 
Systolic blood pressure (mmHg) 123.4 ± 14.1 117.2 ± 10.5 114.8 ± 11.8 
Diastolic blood pressure (mmHg) 72.4 ± 10.5 66.5 ± 8.7 64.2 ± 9.5 
Abnormal blood pressure, (%) 55.6* 10.0 13.3 
Triglycerides (mg/dl) 220.7 ± 88.6* 125.6 ± 55.0 84.6 ± 29.5* 
Abnormal triglycerides (%) 77.8* 25.0 4.4* 
HDL (mg/dl) 34.4 ± 5.7 38.5 ± 11.2 42.8 ± 11.0 
Abnormal HDL (%) 100.0 70.0 68.9 
Fasting glucose (mg/dl) 90.7 ± 5.5 91.7 ± 8.2 84.0 ± 7.0* 
Impaired glucose tolerance (%) 25.0 20.0 13.3 
Glucose disposal rate (mg · kg−1 · min−111.1 ± 3.8 10.6 ± 1.4 15.6 ± 2.2* 
NMR profile (selected)    
 Large VLDL concentration (nmol/l) 6.5 ± 4.1 3.9 ± 4.1 1.4 ± 1.8* 
 VLDL size (nm) 56.7 ± 8.1 54.4 ± 10.1 48.2 ± 8.7* 
 Total LDL concentration (nmol/l) 1,696 ± 469 1,431 ± 424 1,155 ± 287* 
 Large LDL concentration (nmol/l) 353 ± 283 479 ± 379 620 ± 321 
 Small to intermediate LDL (nmol/l) 1,332 ± 489 938 ± 533 523 ± 280* 
 LDL size (nm) 20.4 ± 0.6 20.6 ± 0.7 21.2 ± 0.5* 
 Large HDL concentration (μmol/l) 2.3 ± 1.8 4.3 ± 3.3 7.1 ± 3.3* 
 HDL size (nm) 8.5 ± 0.2 8.6 ± 0.3 9.0 ± 0.4* 

Data are means ± SD, unless otherwise indicated. ATP+, met ATP criteria; ATP, did not meet ATP III criteria.

*

P < 0.05 compared with persons who did not meet ATP III criteria (ATP III) and who were insulin resistant with glucose disposal rate <12 mg·kg−1·min−1.

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