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Table 2—

Serum Cys C and serum Cr concentrations according to hypertension and diabetes status and age of subjects

Age-group
<80 years (n = 1,005)*
≥80 years (n = 248)*
Hypertension
PHypertension
P
NoYesNoYes
Total study population 628 377 — 159 89 — 
    Serum Cys C (mg/l) 0.97 ± 0.23 1.10 ± 0.34 <0.001 1.30 ± 0.49 1.44 ± 0.55 0.002 
    Serum Cr (μmol/l) 90.2 ± 14.5 96.9 ± 20.2 <0.001 98.4 ± 27.7 103.4 ± 29.7 0.045 
No diabetes 569 289 — 135 73 — 
    Serum Cys C (mg/l) 0.97 ± 0.23 1.10 ± 0.35 <0.001 1.24 ± 0.41 1.43 ± 0.55 <0.001 
    Serum Cr (μmol/l) 90.2 ± 14.6 96.4 ± 19.2 <0.001 95.5 ± 22.3 102.1 ± 30.5 0.026 
Diabetes 59 88 — 24 16 — 
    Serum Cys C (mg/l) 1.01 ± 0.24 1.09 ± 0.31 0.050 1.62 ± 0.71 1.47 ± 0.55 NS 
    Serum Cr (μmol/l) 90.6 ± 13.2 98.6 ± 23.1 0.035 115.0 ± 45.0 109.4 ± 26.2 NS 
    Duration of diabetes (years) 4.5 ± 5.1 7.0 ± 6.2 0.009 9.6 ± 7.9 3.9 ± 4.1 0.022 
Age-group
<80 years (n = 1,005)*
≥80 years (n = 248)*
Hypertension
PHypertension
P
NoYesNoYes
Total study population 628 377 — 159 89 — 
    Serum Cys C (mg/l) 0.97 ± 0.23 1.10 ± 0.34 <0.001 1.30 ± 0.49 1.44 ± 0.55 0.002 
    Serum Cr (μmol/l) 90.2 ± 14.5 96.9 ± 20.2 <0.001 98.4 ± 27.7 103.4 ± 29.7 0.045 
No diabetes 569 289 — 135 73 — 
    Serum Cys C (mg/l) 0.97 ± 0.23 1.10 ± 0.35 <0.001 1.24 ± 0.41 1.43 ± 0.55 <0.001 
    Serum Cr (μmol/l) 90.2 ± 14.6 96.4 ± 19.2 <0.001 95.5 ± 22.3 102.1 ± 30.5 0.026 
Diabetes 59 88 — 24 16 — 
    Serum Cys C (mg/l) 1.01 ± 0.24 1.09 ± 0.31 0.050 1.62 ± 0.71 1.47 ± 0.55 NS 
    Serum Cr (μmol/l) 90.6 ± 13.2 98.6 ± 23.1 0.035 115.0 ± 45.0 109.4 ± 26.2 NS 
    Duration of diabetes (years) 4.5 ± 5.1 7.0 ± 6.2 0.009 9.6 ± 7.9 3.9 ± 4.1 0.022 

Data are means ± SD.

*

Five (age <80 years) and two (age ≥80 years) subjects with missing values were excluded;

adjusted for age, sex, use of glucocorticoids, coronary heart disease, and diabetes;

adjusted for age, sex, use of glucocorticoids, and coronary heart disease.

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