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Table 3—

Risk of mortality across fitness categories (quartiles of maximal METs attained during the exercise test) and BMI categories

AdjustmentsFitness quartiles (METs)
P for trend
≤8.828.83–10.08
10.09–11.71
>11.71
RR95% CIRR95% CIRR95% CIRR (ref)
Age, examination year 5.72 (3.54–9.24) 3.01 (1.84–4.93) 1.64 (0.97–2.79) 1.0 <0.0001 
Above + nonmodifiable risk factors* 5.23 (3.22–8.49) 2.93 (1.79–4.80) 1.62 (0.95–2.75) 1.0 <0.0001 
Above + modifiable risk factors 4.29 (2.61–7.05) 2.68 (1.62–4.44) 1.58 (0.92–2.70) 1.0 <0.0001 
Above + BMI 4.49 (2.64–7.64) 2.77 (1.65–4.66) 1.60 (0.93–2.76) 1.0 <0.0001 
AdjustmentsFitness quartiles (METs)
P for trend
≤8.828.83–10.08
10.09–11.71
>11.71
RR95% CIRR95% CIRR95% CIRR (ref)
Age, examination year 5.72 (3.54–9.24) 3.01 (1.84–4.93) 1.64 (0.97–2.79) 1.0 <0.0001 
Above + nonmodifiable risk factors* 5.23 (3.22–8.49) 2.93 (1.79–4.80) 1.62 (0.95–2.75) 1.0 <0.0001 
Above + modifiable risk factors 4.29 (2.61–7.05) 2.68 (1.62–4.44) 1.58 (0.92–2.70) 1.0 <0.0001 
Above + BMI 4.49 (2.64–7.64) 2.77 (1.65–4.66) 1.60 (0.93–2.76) 1.0 <0.0001 
AdjustmentsBMI categories (kg/m2)
P for trend
<25.0
25.0–29.9
≥30.0
RR (ref)RR95% CIRR95% CI
Age, examination year 1.0 1.23 (0.93–1.63) 1.86 (1.34–2.59) 0.0003 
Above + nonmodifiable risk factors* 1.0 1.23 (0.93–1.63) 1.82 (1.31–2.53) 0.0005 
Above + modifiable risk factors 1.0 1.07 (0.81–1.43) 1.51 (1.08–2.10) 0.02 
Above + fitness (treadmill METs) 1.0 0.81 (0.61–1.09) 0.81 (0.56–1.16) 0.22 
AdjustmentsBMI categories (kg/m2)
P for trend
<25.0
25.0–29.9
≥30.0
RR (ref)RR95% CIRR95% CI
Age, examination year 1.0 1.23 (0.93–1.63) 1.86 (1.34–2.59) 0.0003 
Above + nonmodifiable risk factors* 1.0 1.23 (0.93–1.63) 1.82 (1.31–2.53) 0.0005 
Above + modifiable risk factors 1.0 1.07 (0.81–1.43) 1.51 (1.08–2.10) 0.02 
Above + fitness (treadmill METs) 1.0 0.81 (0.61–1.09) 0.81 (0.56–1.16) 0.22 
*

Nonmodifiable risk factors include history of cancer or cardiovascular event or parental history of premature cardiovascular event;

modifiable risk factors include smoking, resting systolic blood pressure, cholesterol, and glucose.

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