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Table 1—

Clinical and metabolic characteristics of 3,776 subjects with type 2 diabetes, categorized according to WBC count quintiles

1st quintile (3.50–5.60)2nd quintile (5.70–6.60)3rd quintile (6.70–7.40)4th quintile (7.50–8.60)5th quintile (8.70–12.50)P
n 723 825 719 742 767 — 
Age (years) 59.4 ± 12.9 58.6 ± 13.0 58.6 ± 13.8 59.0 ± 13.8 59.4 ± 13.8 0.657 
Male (%) 41.1 41.7 45.3 42.9 45.2 0.351 
Smokers (%) 21.3 22.8 28.1 32.0 37.0 <0.001 
Disease duration (years) 7.4 ± 6.1 7.0 ± 6.3 7.2 ± 6.4 7.2 ± 6.6 8.1 ± 7.3 0.046 
Waist (cm) 82.2 ± 9.6 84.9 ± 9.6 85.8 ± 9.7 86.3 ± 10.4 87.4 ± 10.4 <0.001 
BMI (kg/m223.9 ± 3.6 25.0 ± 3.8 25.1 ± 3.9 25.5 ± 4.2 25.6 ± 4.3 <0.001 
Waist-to-hip ratio 0.87 ± 0.07 0.88 ± 0.06 0.89 ± 0.06 0.89 ± 0.07 0.90 ± 0.08 <0.001 
Systolic blood pressure (mmHg) 132 ± 21 135 ± 20 138 ± 22 138 ± 22 138 ± 22 <0.001 
Diastolic blood pressure (mmHg) 75 ± 11 77 ± 11 78 ± 12 78 ± 11 77 ± 11 <0.001 
HbA1c (%) 7.44 ± 1.84 7.70 ± 1.81 7.78 ± 1.81 7.92 ± 1.87 8.08 ± 1.83 <0.001 
Fasting plasma glucose (mmol/l) 8.66 ± 3.51 8.83 ± 3.08 8.93 ± 3.44 9.08 ± 3.51 9.12 ± 3.68 0.004 
Total cholesterol (mmol/l) 5.27 ± 1.31 5.32 ± 1.11 5.42 ± 1.18 5.48 ± 1.24 5.51 ± 1.17 <0.001 
HDL cholesterol (mmol/l) 1.36 ± 0.40 1.27 ± 0.34 1.25 ± 0.37 1.23 ± 0.35 1.19 ± 0.31 <0.001 
LDL cholesterol (mmol/l) 3.26 ± 0.96 3.32 ± 0.88 3.37 ± 1.00 3.42 ± 1.04 3.44 ± 0.98 <0.001 
Triglycerides (mmol/l) 1.08 (0.75–1.56) 1.24 (0.90–1.95) 1.37 (0.96–2.10) 1.48 (1.00–2.24) 1.62 (1.12–2.31) <0.001 
Plasma creatinine (umol/l) 71 (60–86) 72 (60–87) 76 (62–92) 77 (63–94) 78 (64–100) <0.001 
UAE (mg/day) 13.3 (7.59–39.9) 16.1 (8.1–65.1) 22.7 (8.9–96.4) 23.8 (9.8–173.5) 42.8 (12.3–250.9) <0.001 
1st quintile (3.50–5.60)2nd quintile (5.70–6.60)3rd quintile (6.70–7.40)4th quintile (7.50–8.60)5th quintile (8.70–12.50)P
n 723 825 719 742 767 — 
Age (years) 59.4 ± 12.9 58.6 ± 13.0 58.6 ± 13.8 59.0 ± 13.8 59.4 ± 13.8 0.657 
Male (%) 41.1 41.7 45.3 42.9 45.2 0.351 
Smokers (%) 21.3 22.8 28.1 32.0 37.0 <0.001 
Disease duration (years) 7.4 ± 6.1 7.0 ± 6.3 7.2 ± 6.4 7.2 ± 6.6 8.1 ± 7.3 0.046 
Waist (cm) 82.2 ± 9.6 84.9 ± 9.6 85.8 ± 9.7 86.3 ± 10.4 87.4 ± 10.4 <0.001 
BMI (kg/m223.9 ± 3.6 25.0 ± 3.8 25.1 ± 3.9 25.5 ± 4.2 25.6 ± 4.3 <0.001 
Waist-to-hip ratio 0.87 ± 0.07 0.88 ± 0.06 0.89 ± 0.06 0.89 ± 0.07 0.90 ± 0.08 <0.001 
Systolic blood pressure (mmHg) 132 ± 21 135 ± 20 138 ± 22 138 ± 22 138 ± 22 <0.001 
Diastolic blood pressure (mmHg) 75 ± 11 77 ± 11 78 ± 12 78 ± 11 77 ± 11 <0.001 
HbA1c (%) 7.44 ± 1.84 7.70 ± 1.81 7.78 ± 1.81 7.92 ± 1.87 8.08 ± 1.83 <0.001 
Fasting plasma glucose (mmol/l) 8.66 ± 3.51 8.83 ± 3.08 8.93 ± 3.44 9.08 ± 3.51 9.12 ± 3.68 0.004 
Total cholesterol (mmol/l) 5.27 ± 1.31 5.32 ± 1.11 5.42 ± 1.18 5.48 ± 1.24 5.51 ± 1.17 <0.001 
HDL cholesterol (mmol/l) 1.36 ± 0.40 1.27 ± 0.34 1.25 ± 0.37 1.23 ± 0.35 1.19 ± 0.31 <0.001 
LDL cholesterol (mmol/l) 3.26 ± 0.96 3.32 ± 0.88 3.37 ± 1.00 3.42 ± 1.04 3.44 ± 0.98 <0.001 
Triglycerides (mmol/l) 1.08 (0.75–1.56) 1.24 (0.90–1.95) 1.37 (0.96–2.10) 1.48 (1.00–2.24) 1.62 (1.12–2.31) <0.001 
Plasma creatinine (umol/l) 71 (60–86) 72 (60–87) 76 (62–92) 77 (63–94) 78 (64–100) <0.001 
UAE (mg/day) 13.3 (7.59–39.9) 16.1 (8.1–65.1) 22.7 (8.9–96.4) 23.8 (9.8–173.5) 42.8 (12.3–250.9) <0.001 

Data are means ± SD or median (interquartile range).

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