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Table 1—

Baseline characteristics of type 1 and type 2 diabetic patients with different genotypes of the TLR4 polymorphisms

Type 1 diabetic patients
Type 2 diabetic patients
Asp/Asp and Thr/Thr genotypesAsp/Gly and Thr/Ile genotypesPAsp/Asp and Thr/Thr genotypesAsp/Gly and Thr/Ile genotypesP
n 218 26 — 460 65 — 
Diabetes duration (years) 18.7 (17.1–20.4) 20.8 (15.4–26.2) 0.44* 11.5 (10.6–12.3) 10.7 (8.4–12.9) 0.44* 
Female (%) 50 (35.5–64.5) 43 (24–62] 0.54 44 (39.4–48.4) 46.2 (34.0–58.3) 0.79 
Age (years) 46.5 (44.9–48.2) 49.0 (42.8–55.3) 0.51* 65.6 (64.6–66.5) 63.8 (61.2–66.4) 0.14* 
Nicotine use (%) 26 (19.1–32.9) 25 (8–42) 1.00 25.5 (20.6–30.5) 26.3 (12.3–40.3) 1.00 
Hypertension (%) 32.7 (19.1–46.3) 26.9 (24.6–29.2) 0.66 71.8 (67.5–75.9) 66.2 (54.7–77.7) 0.38 
HbA1c (%) 7.3 (7.1–7.5) 7.3 (6.8–7.7) 0.58* 7.5 (7.4–7.7) 7.2 (6.8–7.5) 0.08* 
Cholesterol (mg/dl) 193 (188–198) 194 (179–209) 0.90* 197 (193–201) 193 (180–206) 0.49* 
Triglycerides (mg/dl) 94 (84–103) 81 (63–98) 0.53* 171 (161–180) 173 (138–207) 0.82* 
BMI (kg/m225.4 (24.9–25.9) 25.0 (23.9–26.2) 0.79* 30.2 (29.7–30.7) 30.4 (29.1–31.7) 0.49* 
Type 1 diabetic patients
Type 2 diabetic patients
Asp/Asp and Thr/Thr genotypesAsp/Gly and Thr/Ile genotypesPAsp/Asp and Thr/Thr genotypesAsp/Gly and Thr/Ile genotypesP
n 218 26 — 460 65 — 
Diabetes duration (years) 18.7 (17.1–20.4) 20.8 (15.4–26.2) 0.44* 11.5 (10.6–12.3) 10.7 (8.4–12.9) 0.44* 
Female (%) 50 (35.5–64.5) 43 (24–62] 0.54 44 (39.4–48.4) 46.2 (34.0–58.3) 0.79 
Age (years) 46.5 (44.9–48.2) 49.0 (42.8–55.3) 0.51* 65.6 (64.6–66.5) 63.8 (61.2–66.4) 0.14* 
Nicotine use (%) 26 (19.1–32.9) 25 (8–42) 1.00 25.5 (20.6–30.5) 26.3 (12.3–40.3) 1.00 
Hypertension (%) 32.7 (19.1–46.3) 26.9 (24.6–29.2) 0.66 71.8 (67.5–75.9) 66.2 (54.7–77.7) 0.38 
HbA1c (%) 7.3 (7.1–7.5) 7.3 (6.8–7.7) 0.58* 7.5 (7.4–7.7) 7.2 (6.8–7.5) 0.08* 
Cholesterol (mg/dl) 193 (188–198) 194 (179–209) 0.90* 197 (193–201) 193 (180–206) 0.49* 
Triglycerides (mg/dl) 94 (84–103) 81 (63–98) 0.53* 171 (161–180) 173 (138–207) 0.82* 
BMI (kg/m225.4 (24.9–25.9) 25.0 (23.9–26.2) 0.79* 30.2 (29.7–30.7) 30.4 (29.1–31.7) 0.49* 

Data are means (asymptotic 95% CI).

*

Mann-Whitney U test;

Fisher’s exact test.

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