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Table 2—

Frequencies and rates of genotypes of TLR4 polymorphisms in type 1 and type 2 diabetic patients with nephropathy and neuropathy

Type 1 diabetes
Type 2 diabetes
Asp/Asp and Thr/Thr genotypesAsp/Gly and Thr/Ile genotypesPORAsp/Asp and Thr/Thr genotypesAsp/Gly and Thr/Ile genotypesPOR
Nephropathy (%) 51 (23.2%) 5 (19.2%) 0.81 0.79 (0.28–2.20) 183 (39.4%) 23 (35.4%) 0.59 0.84 (0.49–1.45) 
Neuropathy (%) 64 (29.1%) 7 (26.9%) 1.00 0.90 (0.36–2.24) 236 (50.9%) 17 (26.2%) 0.0002 0.34 (0.19–0.61) 
Type 1 diabetes
Type 2 diabetes
Asp/Asp and Thr/Thr genotypesAsp/Gly and Thr/Ile genotypesPORAsp/Asp and Thr/Thr genotypesAsp/Gly and Thr/Ile genotypesPOR
Nephropathy (%) 51 (23.2%) 5 (19.2%) 0.81 0.79 (0.28–2.20) 183 (39.4%) 23 (35.4%) 0.59 0.84 (0.49–1.45) 
Neuropathy (%) 64 (29.1%) 7 (26.9%) 1.00 0.90 (0.36–2.24) 236 (50.9%) 17 (26.2%) 0.0002 0.34 (0.19–0.61) 

Data are means (asymptotic 95% CI) unless otherwise noted. P calculated with Fisher’s exact test.

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