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Table 1—

Demographic and metabolic parameters at the time of metabolic testing during the third trimester (antepartum) and 15 months after delivery (postpartum) in women with GDM who subsequently remained nonpreeclamptic and those who developed preeclampsia

Antepartum clinical parametersNonpreeclampticPreeclampsiaP
n 121 (80.7%) 29 (19.3%)  
Age 30.5 ± 5.6 30.1 ± 6.2 NS 
Nulliparous 20 (16.4%) 11 (37.9%) 0.01 
First-degree relative with diabetes 28 (30.8%) 6 (27.3%) NS 
Birthweight of largest prior infant (lb) 8.0 ± 1.3 8.2 ± 1.5 NS 
Prepregnancy weight (lb) 148.8 ± 29.0 153.5 ± 28.5 NS 
Prepregnancy BMI (kg/m228.9 ± 5.0 28.6 ± 5.2 NS 
1-h 50-g glucose challenge test (mg/dl) 170.1 ± 35.3 165.4 ± 37.7 NS 
Highest fasting plasma glucose (mg/dl) 101.8 ± 18.5 103.9 ± 10.6 NS 
Required insulin during pregnancy 18 (19.8%) 5 (22.7%) NS 
Preterm delivery (<37 weeks) 17 (13.9%) 3 (10.3%) NS 
Antepartum entry (early third trimester)    
    Gestational age at entry (weeks) 30.9 ± 2.3 31.3 ± 2.5 NS 
    Height (in) 60.1 ± 2.3 61.5 ± 2.4 0.003 
    Maternal weight (entry, lb) 164.4 ± 30.3 170.5 ± 31.9 NS 
    BMI (entry, kg/m231.9 ± 5.1 31.8 ± 5.8 NS 
    SBP (mmHg) 103.1 ± 6.9 112.1 ± 10.0 <0.0001 
    DBP (mmHg) 58.9 ± 4.6 64.4 ± 8.8 0.002 
    Mean arterial blood pressure (mmHg) 73.6 ± 4.7 80.3 ± 8.6 0.003 
Postpartum (15 months after delivery) 70 (78.7%) 19 (21.3%)  
    SBP (mmHg) 106.3 ± 8.2 114.1 ± 11.7 0.01 
    DBP (mmHg) 62.2 ± 5.9 65.7 ± 8.0 0.04 
    Mean arterial blood pressure (mmHg) 76.9 ± 6.1 81.8 ± 8.7 0.03 
Antepartum clinical parametersNonpreeclampticPreeclampsiaP
n 121 (80.7%) 29 (19.3%)  
Age 30.5 ± 5.6 30.1 ± 6.2 NS 
Nulliparous 20 (16.4%) 11 (37.9%) 0.01 
First-degree relative with diabetes 28 (30.8%) 6 (27.3%) NS 
Birthweight of largest prior infant (lb) 8.0 ± 1.3 8.2 ± 1.5 NS 
Prepregnancy weight (lb) 148.8 ± 29.0 153.5 ± 28.5 NS 
Prepregnancy BMI (kg/m228.9 ± 5.0 28.6 ± 5.2 NS 
1-h 50-g glucose challenge test (mg/dl) 170.1 ± 35.3 165.4 ± 37.7 NS 
Highest fasting plasma glucose (mg/dl) 101.8 ± 18.5 103.9 ± 10.6 NS 
Required insulin during pregnancy 18 (19.8%) 5 (22.7%) NS 
Preterm delivery (<37 weeks) 17 (13.9%) 3 (10.3%) NS 
Antepartum entry (early third trimester)    
    Gestational age at entry (weeks) 30.9 ± 2.3 31.3 ± 2.5 NS 
    Height (in) 60.1 ± 2.3 61.5 ± 2.4 0.003 
    Maternal weight (entry, lb) 164.4 ± 30.3 170.5 ± 31.9 NS 
    BMI (entry, kg/m231.9 ± 5.1 31.8 ± 5.8 NS 
    SBP (mmHg) 103.1 ± 6.9 112.1 ± 10.0 <0.0001 
    DBP (mmHg) 58.9 ± 4.6 64.4 ± 8.8 0.002 
    Mean arterial blood pressure (mmHg) 73.6 ± 4.7 80.3 ± 8.6 0.003 
Postpartum (15 months after delivery) 70 (78.7%) 19 (21.3%)  
    SBP (mmHg) 106.3 ± 8.2 114.1 ± 11.7 0.01 
    DBP (mmHg) 62.2 ± 5.9 65.7 ± 8.0 0.04 
    Mean arterial blood pressure (mmHg) 76.9 ± 6.1 81.8 ± 8.7 0.03 

Data are means ± SD and n (%). NS, no significant difference between non-preeclamptic and preeclampsia groups.

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