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Table 2—

Total and differential leukocyte counts of study subjects

NormoalbuminuriaMicroalbuminuriaOvert nephropathyP
n 888 326 266 — 
WBC count (109/l)     
    Means ± SD 6,572 ± 1,647 6,984 ± 1,662 7,440 ± 1,769 <0.0001 
    Adjusted mean 6,555 6,962 7,407 <0.0001 
Neutrophil count (109/l)     
    Means ± SD 3,730 ± 1,283 4,101 ± 1,432 4,742 ± 1,590 <0.0001 
    Adjusted mean 3,728 4,074 4,660 <0.0001 
Monocyte count (109/l)     
    Means ± SD 440 ± 158 482 ± 173 553 ± 237 <0.0001 
    Adjusted mean 445 483 544 <0.0001 
Lymphocyte count (109/l)     
    Means ± SD 2,222 ± 736 2,206 ± 701 1,937 ± 769 <0.001 
    Adjusted mean 2,197 2,206 1,997 0.0003 
Eosinophil count (109/l)     
    Means ± SD 152 ± 139 171 ± 245 194 ± 146 0.002 
    Adjusted mean 157 175 191 0.017 
Basophil count (109/l)     
    Means ± SD 32 ± 19 35 ± 21 36 ± 25 0.040 
    Adjusted mean 32 35 36 0.031 
Plasma leptin (ng/ml)* 7.8 ± 6.8 10.6 ± 9.1 15.8 ± 17.9 0.014 
NormoalbuminuriaMicroalbuminuriaOvert nephropathyP
n 888 326 266 — 
WBC count (109/l)     
    Means ± SD 6,572 ± 1,647 6,984 ± 1,662 7,440 ± 1,769 <0.0001 
    Adjusted mean 6,555 6,962 7,407 <0.0001 
Neutrophil count (109/l)     
    Means ± SD 3,730 ± 1,283 4,101 ± 1,432 4,742 ± 1,590 <0.0001 
    Adjusted mean 3,728 4,074 4,660 <0.0001 
Monocyte count (109/l)     
    Means ± SD 440 ± 158 482 ± 173 553 ± 237 <0.0001 
    Adjusted mean 445 483 544 <0.0001 
Lymphocyte count (109/l)     
    Means ± SD 2,222 ± 736 2,206 ± 701 1,937 ± 769 <0.001 
    Adjusted mean 2,197 2,206 1,997 0.0003 
Eosinophil count (109/l)     
    Means ± SD 152 ± 139 171 ± 245 194 ± 146 0.002 
    Adjusted mean 157 175 191 0.017 
Basophil count (109/l)     
    Means ± SD 32 ± 19 35 ± 21 36 ± 25 0.040 
    Adjusted mean 32 35 36 0.031 
Plasma leptin (ng/ml)* 7.8 ± 6.8 10.6 ± 9.1 15.8 ± 17.9 0.014 

See definition of normo- and microalbuminuria and overt nephropathy in research design and methods. Adjusted means were adjusted by sex, age, BMI, WHR, and smoking status. *Plasma leptin levels were measured in 50 normoalbuminuric, 50 microalbuminuric, and 63 overt nephropathic subjects.

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