Correlation of fasting to clamp-derived indices of insulin secretion, sensitivity, and clearance.
. | Spearman coefficient (r) . | P . |
---|---|---|
Indices of pancreatic β-cell secretion | ||
Fasting insulin: first-phase insulin | 0.85 | <0.05 |
Fasting insulin: steady-phase insulin | 0.79 | <0.05 |
Fasting C-peptide: first-phase insulin | 0.59 | <0.05 |
Fasting C-peptide: steady-phase insulin | 0.72 | <0.05 |
Fasting C-peptide: first-phase C-peptide | 0.59 | <0.05 |
Fasting C-peptide: steady-phase C-peptide | 0.70 | <0.05 |
Insulinogenic index: first-phase insulin | 0.86 | <0.05 |
Insulinogenic index: steady-phase insulin | 0.80 | <0.05 |
HOMA-B%: first-phase insulin | 0.69 | <0.05 |
HOMA-B%: steady-phase insulin | 0.72 | <0.05 |
Indices of glycemic insulin sensitivity and resistance | ||
HOMA-IR: SIEug clamp | −0.51 | <0.05 |
HOMA-IR: SIHyper clamp | −0.56 | <0.05 |
Quicki: SIEug clamp | 0.69 | <0.05 |
Quicki: SIHyper clamp | 0.67 | <0.05 |
Glucose/insulin: SIEug clamp | 0.37 | <0.05 |
Glucose/insulin: SIHyper clamp | 0.42 | <0.05 |
Indices of insulin sensitivity as an antilipolytic | ||
ISI FFA: % FFA suppression (first phase) | 0.008 | 0.16 |
ISI FFA: % FFA suppression (steady phase) | −0.04 | 0.14 |
ISI FFA: % total FFA suppression (euglycemic clamp) | 0.22 | 0.09 |
Indices of insulin clearance | ||
Fasting C-peptide/insulin: MCR insulin | 0.09 | 0.80 |
Fasting C-peptide/insulin: first-phase C-peptide/insulin | 0.52 | <0.05 |
Fasting C-peptide/insulin: steady-phase C-peptide/insulin | 0.30 | 0.07 |
. | Spearman coefficient (r) . | P . |
---|---|---|
Indices of pancreatic β-cell secretion | ||
Fasting insulin: first-phase insulin | 0.85 | <0.05 |
Fasting insulin: steady-phase insulin | 0.79 | <0.05 |
Fasting C-peptide: first-phase insulin | 0.59 | <0.05 |
Fasting C-peptide: steady-phase insulin | 0.72 | <0.05 |
Fasting C-peptide: first-phase C-peptide | 0.59 | <0.05 |
Fasting C-peptide: steady-phase C-peptide | 0.70 | <0.05 |
Insulinogenic index: first-phase insulin | 0.86 | <0.05 |
Insulinogenic index: steady-phase insulin | 0.80 | <0.05 |
HOMA-B%: first-phase insulin | 0.69 | <0.05 |
HOMA-B%: steady-phase insulin | 0.72 | <0.05 |
Indices of glycemic insulin sensitivity and resistance | ||
HOMA-IR: SIEug clamp | −0.51 | <0.05 |
HOMA-IR: SIHyper clamp | −0.56 | <0.05 |
Quicki: SIEug clamp | 0.69 | <0.05 |
Quicki: SIHyper clamp | 0.67 | <0.05 |
Glucose/insulin: SIEug clamp | 0.37 | <0.05 |
Glucose/insulin: SIHyper clamp | 0.42 | <0.05 |
Indices of insulin sensitivity as an antilipolytic | ||
ISI FFA: % FFA suppression (first phase) | 0.008 | 0.16 |
ISI FFA: % FFA suppression (steady phase) | −0.04 | 0.14 |
ISI FFA: % total FFA suppression (euglycemic clamp) | 0.22 | 0.09 |
Indices of insulin clearance | ||
Fasting C-peptide/insulin: MCR insulin | 0.09 | 0.80 |
Fasting C-peptide/insulin: first-phase C-peptide/insulin | 0.52 | <0.05 |
Fasting C-peptide/insulin: steady-phase C-peptide/insulin | 0.30 | 0.07 |