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Table 4—

Correlation of fasting to clamp-derived indices of insulin secretion, sensitivity, and clearance.

Spearman coefficient (r)P
Indices of pancreatic β-cell secretion   
 Fasting insulin: first-phase insulin 0.85 <0.05 
 Fasting insulin: steady-phase insulin 0.79 <0.05 
 Fasting C-peptide: first-phase insulin 0.59 <0.05 
 Fasting C-peptide: steady-phase insulin 0.72 <0.05 
 Fasting C-peptide: first-phase C-peptide 0.59 <0.05 
 Fasting C-peptide: steady-phase C-peptide 0.70 <0.05 
 Insulinogenic index: first-phase insulin 0.86 <0.05 
 Insulinogenic index: steady-phase insulin 0.80 <0.05 
 HOMA-B%: first-phase insulin 0.69 <0.05 
 HOMA-B%: steady-phase insulin 0.72 <0.05 
Indices of glycemic insulin sensitivity and resistance   
 HOMA-IR: SIEug clamp −0.51 <0.05 
 HOMA-IR: SIHyper clamp −0.56 <0.05 
 Quicki: SIEug clamp 0.69 <0.05 
 Quicki: SIHyper clamp 0.67 <0.05 
 Glucose/insulin: SIEug clamp 0.37 <0.05 
 Glucose/insulin: SIHyper clamp 0.42 <0.05 
Indices of insulin sensitivity as an antilipolytic   
 ISI FFA: % FFA suppression (first phase) 0.008 0.16 
 ISI FFA: % FFA suppression (steady phase) −0.04 0.14 
 ISI FFA: % total FFA suppression (euglycemic clamp) 0.22 0.09 
Indices of insulin clearance   
 Fasting C-peptide/insulin: MCR insulin 0.09 0.80 
 Fasting C-peptide/insulin: first-phase C-peptide/insulin 0.52 <0.05 
 Fasting C-peptide/insulin: steady-phase C-peptide/insulin 0.30 0.07 
Spearman coefficient (r)P
Indices of pancreatic β-cell secretion   
 Fasting insulin: first-phase insulin 0.85 <0.05 
 Fasting insulin: steady-phase insulin 0.79 <0.05 
 Fasting C-peptide: first-phase insulin 0.59 <0.05 
 Fasting C-peptide: steady-phase insulin 0.72 <0.05 
 Fasting C-peptide: first-phase C-peptide 0.59 <0.05 
 Fasting C-peptide: steady-phase C-peptide 0.70 <0.05 
 Insulinogenic index: first-phase insulin 0.86 <0.05 
 Insulinogenic index: steady-phase insulin 0.80 <0.05 
 HOMA-B%: first-phase insulin 0.69 <0.05 
 HOMA-B%: steady-phase insulin 0.72 <0.05 
Indices of glycemic insulin sensitivity and resistance   
 HOMA-IR: SIEug clamp −0.51 <0.05 
 HOMA-IR: SIHyper clamp −0.56 <0.05 
 Quicki: SIEug clamp 0.69 <0.05 
 Quicki: SIHyper clamp 0.67 <0.05 
 Glucose/insulin: SIEug clamp 0.37 <0.05 
 Glucose/insulin: SIHyper clamp 0.42 <0.05 
Indices of insulin sensitivity as an antilipolytic   
 ISI FFA: % FFA suppression (first phase) 0.008 0.16 
 ISI FFA: % FFA suppression (steady phase) −0.04 0.14 
 ISI FFA: % total FFA suppression (euglycemic clamp) 0.22 0.09 
Indices of insulin clearance   
 Fasting C-peptide/insulin: MCR insulin 0.09 0.80 
 Fasting C-peptide/insulin: first-phase C-peptide/insulin 0.52 <0.05 
 Fasting C-peptide/insulin: steady-phase C-peptide/insulin 0.30 0.07 
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