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Table 3—

Hemodynamic and renal parameters during placeboRS and placeboLS

ParameterPlaceboRS
PlaceboLS
Δ PlaceboLS − Δ placeboRS
P
Week 2Week 4Δ Week 4–2Week 2Week 4Δ Week 4–2Δ
Blood pressure (mmHg)         
 24-h         
  Systolic 138.6 ± 4.2 137.5 ± 4.0 −1.1 ± 2.1 131.9 ± 4.5 132.6 ± 4.6 0.7 ± 2.7 1.8 (−5.9 to 9.5) NS 
  Diastolic 81.9 ± 3.1 80.9 ± 2.7 −1 ± 1.1 77.3 ± 1.9 79.6 ± 2.7 2.3 ± 1.9 3.3 (−1.7 to 8.3) NS 
  Mean arterial pressure 100.8 ± 2.9 100.4 ± 2.8 −0.4 ± 1.5 97.5 ± 2.9 97.0 ± 2.8 −0.5 ± 2.0 −0.1 (−5.9 to 5.7) NS 
 Awake         
  Systolic 141.8 ± 4.4 141.5 ± 4.1 −0.3 ± 2.4 135.1 ± 4.7 135.1 ± 4.8 0 ± 2.7 0.3 (−7.9 to 8.5) NS 
  Diastolic 84.2 ± 3.3 83.4 ± 2.7 −0.8 ± 1.3 82.3 ± 3.0 81.7 ± 2.9 −0.6 ± 1.8 0.2 (−4.6 to 5.0) NS 
  Mean arterial pressure 103.2 ± 3.2 103.1 ± 2.9 −0.1 ± 1.8 100.3 ± 3.0 98.9 ± 3.1 −1.4 ± 2.2 −1.3 (−7.7 to 5.1) NS 
 Sleep         
  Systolic 124.8 ± 4.1 122.2 ± 3.6 −2.6 ± 2.4 121.0 ± 4.1 122.4 ± 3.8 1.4 ± 3.0 4.0 (−3.7 to 11.7) NS 
  Diastolic 72.4 ± 3.3 71.4 ± 2.4 −1.0 ± 1.7 67.8 ± 1.9 72.1 ± 2.9 4.3 ± 2.5 5.3 (−2.0 to 12.6) NS 
  Mean arterial pressure 93.3 ± 3.1 89.7 ± 2.5 −1.6 ± 1.4 88.1 ± 2.5 89.4 ± 2.5 1.3 ± 2.1 2.9 (−3.3 to 9.1) NS 
GFR (ml · min−1 · 1.73 m−2100.7 ± 5.4 100.5 ± 4.0 −0.2 ± 2.1 99.0 ± 4.7 95.0 ± 4.6 −4.0 ± 2.0 −3.8 (−9.4 to 1.9) NS 
MAG-3 ERPF (ml · min−1 · 1.73 m−2270.7 ± 20.8 276.3 ± 19.1 5.6 ± 14.9 267.7 ± 21.5 272.0 ± 20.2 4.3 ± 15 −1.3 (−53 to 50) NS 
FF (%) 20.3 ± 1.2 19.7 ± 0.8 −0.6 ± 1.2 20.2 ± 1.1 18.9 ± 0.7 −1.3 ± 1.0 −0.8 (−4.7 to 3.1) NS 
PGC (mmHg) 42.5 ± 2.6 41.0 ± 3.7 −1.5 ± 2.0 39.0 ± 2.9 36.4 ± 3.3 −2.5 ± 2.5 −1.0 (−7.8 to 5.7) NS 
ParameterPlaceboRS
PlaceboLS
Δ PlaceboLS − Δ placeboRS
P
Week 2Week 4Δ Week 4–2Week 2Week 4Δ Week 4–2Δ
Blood pressure (mmHg)         
 24-h         
  Systolic 138.6 ± 4.2 137.5 ± 4.0 −1.1 ± 2.1 131.9 ± 4.5 132.6 ± 4.6 0.7 ± 2.7 1.8 (−5.9 to 9.5) NS 
  Diastolic 81.9 ± 3.1 80.9 ± 2.7 −1 ± 1.1 77.3 ± 1.9 79.6 ± 2.7 2.3 ± 1.9 3.3 (−1.7 to 8.3) NS 
  Mean arterial pressure 100.8 ± 2.9 100.4 ± 2.8 −0.4 ± 1.5 97.5 ± 2.9 97.0 ± 2.8 −0.5 ± 2.0 −0.1 (−5.9 to 5.7) NS 
 Awake         
  Systolic 141.8 ± 4.4 141.5 ± 4.1 −0.3 ± 2.4 135.1 ± 4.7 135.1 ± 4.8 0 ± 2.7 0.3 (−7.9 to 8.5) NS 
  Diastolic 84.2 ± 3.3 83.4 ± 2.7 −0.8 ± 1.3 82.3 ± 3.0 81.7 ± 2.9 −0.6 ± 1.8 0.2 (−4.6 to 5.0) NS 
  Mean arterial pressure 103.2 ± 3.2 103.1 ± 2.9 −0.1 ± 1.8 100.3 ± 3.0 98.9 ± 3.1 −1.4 ± 2.2 −1.3 (−7.7 to 5.1) NS 
 Sleep         
  Systolic 124.8 ± 4.1 122.2 ± 3.6 −2.6 ± 2.4 121.0 ± 4.1 122.4 ± 3.8 1.4 ± 3.0 4.0 (−3.7 to 11.7) NS 
  Diastolic 72.4 ± 3.3 71.4 ± 2.4 −1.0 ± 1.7 67.8 ± 1.9 72.1 ± 2.9 4.3 ± 2.5 5.3 (−2.0 to 12.6) NS 
  Mean arterial pressure 93.3 ± 3.1 89.7 ± 2.5 −1.6 ± 1.4 88.1 ± 2.5 89.4 ± 2.5 1.3 ± 2.1 2.9 (−3.3 to 9.1) NS 
GFR (ml · min−1 · 1.73 m−2100.7 ± 5.4 100.5 ± 4.0 −0.2 ± 2.1 99.0 ± 4.7 95.0 ± 4.6 −4.0 ± 2.0 −3.8 (−9.4 to 1.9) NS 
MAG-3 ERPF (ml · min−1 · 1.73 m−2270.7 ± 20.8 276.3 ± 19.1 5.6 ± 14.9 267.7 ± 21.5 272.0 ± 20.2 4.3 ± 15 −1.3 (−53 to 50) NS 
FF (%) 20.3 ± 1.2 19.7 ± 0.8 −0.6 ± 1.2 20.2 ± 1.1 18.9 ± 0.7 −1.3 ± 1.0 −0.8 (−4.7 to 3.1) NS 
PGC (mmHg) 42.5 ± 2.6 41.0 ± 3.7 −1.5 ± 2.0 39.0 ± 2.9 36.4 ± 3.3 −2.5 ± 2.5 −1.0 (−7.8 to 5.7) NS 

Data means ± SEM or mean difference (95% CI).

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