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Table 2—

Demographic, clinical, and biochemical characteristics of those type 1 diabetic subjects without and with significant CAC (with a CAC score of 10 as the categorical divide)

CAC ≤10CAC >10P value
n 28 20  
Age (years) 32 (26–40) 51 (46–55) <0.0001* 
Sex (male/female) 16/12 12/8 1.000 
BMI (kg/m224.2 (22.6–25.6) 26.0 (22.7–27.8) 0.104 
Smokers (ever/never) 10/18 10/10 0.382 
Systolic BP (mmHg) 126 (113–134) 141 (122–154) 0.012* 
Systolic BP (low/high) 16/12 5/15 0.040* 
Diastolic BP (mmHg) 80 (71–86) 74 (70–85) 0.369 
Diastolic BP (low/high) 13/15 8/12 0.771 
Duration of diabetes (years) 16 (7–20) 32 (17–40) 0.0002* 
Retinopathy (present/absent) 12/16 13/7 0.140 
Microalbuminuria (present/absent) 7/21 10/10 0.125 
Neuropathy (present/absent) 6/22 6/14 0.520 
HbA1c (%) 7.4 (6.4–8.5) 8.1 (7.4–9.0) 0.053 
Fasting glucose (mmol/l) 10.3 (6.8–14.1) 11.6 (9.8–16.8) 0.202 
Total cholesterol (mmol/l) 4.90 (4.36–5.56) 5.41 (4.87–6.10) 0.039* 
Triglycerides (mmol/l) 0.91 (0.67–1.32) 1.04 (0.78–1.37) 0.421 
HDL cholesterol (mmol/l) 1.44 (1.15–1.80) 1.33 (1.13–1.60) 0.537 
Creatinine (μmol/l) 102 (93–107) 109 (103–120) 0.003* 
Urinary albumin–to–creatinine ratio 0.5 (0.4–2.0) 2.4 (0.6–6.1) 0.022* 
TAS (mmol/l) 1.31 (1.23–1.36) 1.25 (1.20–1.28) 0.018* 
TAS (low/high) 9/19 15/5 0.0077* 
CAC ≤10CAC >10P value
n 28 20  
Age (years) 32 (26–40) 51 (46–55) <0.0001* 
Sex (male/female) 16/12 12/8 1.000 
BMI (kg/m224.2 (22.6–25.6) 26.0 (22.7–27.8) 0.104 
Smokers (ever/never) 10/18 10/10 0.382 
Systolic BP (mmHg) 126 (113–134) 141 (122–154) 0.012* 
Systolic BP (low/high) 16/12 5/15 0.040* 
Diastolic BP (mmHg) 80 (71–86) 74 (70–85) 0.369 
Diastolic BP (low/high) 13/15 8/12 0.771 
Duration of diabetes (years) 16 (7–20) 32 (17–40) 0.0002* 
Retinopathy (present/absent) 12/16 13/7 0.140 
Microalbuminuria (present/absent) 7/21 10/10 0.125 
Neuropathy (present/absent) 6/22 6/14 0.520 
HbA1c (%) 7.4 (6.4–8.5) 8.1 (7.4–9.0) 0.053 
Fasting glucose (mmol/l) 10.3 (6.8–14.1) 11.6 (9.8–16.8) 0.202 
Total cholesterol (mmol/l) 4.90 (4.36–5.56) 5.41 (4.87–6.10) 0.039* 
Triglycerides (mmol/l) 0.91 (0.67–1.32) 1.04 (0.78–1.37) 0.421 
HDL cholesterol (mmol/l) 1.44 (1.15–1.80) 1.33 (1.13–1.60) 0.537 
Creatinine (μmol/l) 102 (93–107) 109 (103–120) 0.003* 
Urinary albumin–to–creatinine ratio 0.5 (0.4–2.0) 2.4 (0.6–6.1) 0.022* 
TAS (mmol/l) 1.31 (1.23–1.36) 1.25 (1.20–1.28) 0.018* 
TAS (low/high) 9/19 15/5 0.0077* 

Values are n or median (IQ range), unless otherwise stated.

*

P < 0.05. BP, blood pressure.

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