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Table 1—

Clinical characteristics and serum AGEs of control subjects and diabetic patients

Control subjectsDiabetic subjects
n 83 170 
Male/female (%) 51/49 51/49 
Age (years) 52.8 ± 7.5 54.5 ± 8.8 
BMI (kg/m225.0 ± 3.4 26.1 ± 3.7* 
Smokers (%) 13 14 
Duration of diabetes (years) — 9.8 ± 6.8 
Fasting glucose (mmol/l) 5.3 ± 1.2 8.3 ± 2.1 
HbA1c (%) 5.8 ± 0.7 8.1 ± 1.2 
AGEs (unit/ml) 3.1 ± 0.8 4.6 ± 0.7 
Total cholesterol (mmol/l) 5.6 ± 0.9 5.8 ± 1.0 
Triglycerides (mmol/l) 1.3 (0.8) 1.5 (0.9)* 
LDL (mmol/l) 3.6 ± 0.8 3.9 ± 1.0 
HDL (mmol/l) 1.3 ± 0.4 1.2 ± 0.3* 
Systolic blood pressure (mmHg) 126.4 ± 16.3 130.4 ± 12.1* 
Diastolic blood pressure (mmHg) 78.4 ± 10.9 76.0 ± 8.7 
Control subjectsDiabetic subjects
n 83 170 
Male/female (%) 51/49 51/49 
Age (years) 52.8 ± 7.5 54.5 ± 8.8 
BMI (kg/m225.0 ± 3.4 26.1 ± 3.7* 
Smokers (%) 13 14 
Duration of diabetes (years) — 9.8 ± 6.8 
Fasting glucose (mmol/l) 5.3 ± 1.2 8.3 ± 2.1 
HbA1c (%) 5.8 ± 0.7 8.1 ± 1.2 
AGEs (unit/ml) 3.1 ± 0.8 4.6 ± 0.7 
Total cholesterol (mmol/l) 5.6 ± 0.9 5.8 ± 1.0 
Triglycerides (mmol/l) 1.3 (0.8) 1.5 (0.9)* 
LDL (mmol/l) 3.6 ± 0.8 3.9 ± 1.0 
HDL (mmol/l) 1.3 ± 0.4 1.2 ± 0.3* 
Systolic blood pressure (mmHg) 126.4 ± 16.3 130.4 ± 12.1* 
Diastolic blood pressure (mmHg) 78.4 ± 10.9 76.0 ± 8.7 

Data are n or means ± SD except for triglyceride levels, which are given as median (interquartile range).

*

P < 0.05,

P < 0.01 vs. control subjects.

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