Baseline characteristics
| . | Vitamin C treatment group . | Control group . | P value . |
|---|---|---|---|
| n (men/women) | 19 (17/2) | 20 (17/3) | |
| Age (years) | 63.3 ± 2.7 | 67.4 ± 2.1 | 0.444 |
| Duration of diabetes (years) | 11.4 ± 1.1 | 11.5 ± 1.8 | 0.870 |
| BMI (kg/m2) | 27.6 ± 0.61 | 26.5 ± 0.53 | 0.214 |
| Baseline flow 1 (ml · 100 ml−1 · min−1) | 4.28 ± 0.36 | 4.29 ± 0.32 | 0.857 |
| Maximum hyperemia flow (ml · 100 ml−1 · min−1) | 6.8 ± 0.44 | 6.04 ± 0.42 | 0.270 |
| RH% (%) | 51.8 ± 4.7 | 43.8 ± 4.7 | 0.158 |
| Baseline flow 2 (ml · 100 ml−1 · min−1) | 3.94 ± 0.23 | 4.08 ± 0.31 | 0.938 |
| Maximum flow after nitrate (ml · 100 ml−1 · min−1) | 6.56 ± 0.33 | 6.42 ± 0.44 | 0.406 |
| NTG% (%) | 66.3 ± 6.75 | 60.8 ± 6.9 | 0.563 |
| Vitamin C (μmol/l) | 39.9 ± 2.0 | 39.5 ± 2.1 | 0.667 |
| AT III (%) | 82.3 ± 3.2 | 84.6 ± 3.3 | 0.422 |
| protein C (%) | 103.7 ± 5.1 | 87.9 ± 8.8 | 0.695 |
| protein S (%) | 96.2 ± 4.6 | 89.8 ± 6.0 | 0.268 |
| fV (%) | 144.6 ± 5.7 | 127.7 ± 10.3 | 0.822 |
| fVII (%) | 100.3 ± 8.8 | 71.9 ± 9.0 | 0.202 |
| Von Willebrand factor (%) | 133.5 ± 14.5 | 141.0 ± 27 | 0.888 |
| PAI-1 (IU/l) | 3.06 ± 0.36 | 2.18 ± 0.40 | 0.202 |
| tPA (ng/ml) | 12.3 ± 0.99 | 12.2 ± 1.3 | 0.621 |
| Total cholesterol (mg/dl) | 217 ± 12 | 215 ± 9 | 0.749 |
| HDL (mg/dl) | 37.3 ± 2.0 | 36.1 ± 2.2 | 0.496 |
| Fasting glucose (mg/dl) | 131 ± 17 | 158 ± 14 | 0.379 |
| Triglycerides (mg/dl) | 145 ± 10 | 141 ± 13 | 0.550 |
| . | Vitamin C treatment group . | Control group . | P value . |
|---|---|---|---|
| n (men/women) | 19 (17/2) | 20 (17/3) | |
| Age (years) | 63.3 ± 2.7 | 67.4 ± 2.1 | 0.444 |
| Duration of diabetes (years) | 11.4 ± 1.1 | 11.5 ± 1.8 | 0.870 |
| BMI (kg/m2) | 27.6 ± 0.61 | 26.5 ± 0.53 | 0.214 |
| Baseline flow 1 (ml · 100 ml−1 · min−1) | 4.28 ± 0.36 | 4.29 ± 0.32 | 0.857 |
| Maximum hyperemia flow (ml · 100 ml−1 · min−1) | 6.8 ± 0.44 | 6.04 ± 0.42 | 0.270 |
| RH% (%) | 51.8 ± 4.7 | 43.8 ± 4.7 | 0.158 |
| Baseline flow 2 (ml · 100 ml−1 · min−1) | 3.94 ± 0.23 | 4.08 ± 0.31 | 0.938 |
| Maximum flow after nitrate (ml · 100 ml−1 · min−1) | 6.56 ± 0.33 | 6.42 ± 0.44 | 0.406 |
| NTG% (%) | 66.3 ± 6.75 | 60.8 ± 6.9 | 0.563 |
| Vitamin C (μmol/l) | 39.9 ± 2.0 | 39.5 ± 2.1 | 0.667 |
| AT III (%) | 82.3 ± 3.2 | 84.6 ± 3.3 | 0.422 |
| protein C (%) | 103.7 ± 5.1 | 87.9 ± 8.8 | 0.695 |
| protein S (%) | 96.2 ± 4.6 | 89.8 ± 6.0 | 0.268 |
| fV (%) | 144.6 ± 5.7 | 127.7 ± 10.3 | 0.822 |
| fVII (%) | 100.3 ± 8.8 | 71.9 ± 9.0 | 0.202 |
| Von Willebrand factor (%) | 133.5 ± 14.5 | 141.0 ± 27 | 0.888 |
| PAI-1 (IU/l) | 3.06 ± 0.36 | 2.18 ± 0.40 | 0.202 |
| tPA (ng/ml) | 12.3 ± 0.99 | 12.2 ± 1.3 | 0.621 |
| Total cholesterol (mg/dl) | 217 ± 12 | 215 ± 9 | 0.749 |
| HDL (mg/dl) | 37.3 ± 2.0 | 36.1 ± 2.2 | 0.496 |
| Fasting glucose (mg/dl) | 131 ± 17 | 158 ± 14 | 0.379 |
| Triglycerides (mg/dl) | 145 ± 10 | 141 ± 13 | 0.550 |
Data are means ± SE. There were no significant differences between the two groups.