Multivariate survival analysis examining maternal vitamin D intake via food during pregnancy and risk of IA and persistent IA
| Risk factors* . | IA adjusted HR (95% CI) . | Wald χ2 P . | Persistent IA adjusted HR (95% CI) . | Wald χ2 P . |
|---|---|---|---|---|
| n | 16 | 11 | ||
| Vitamin D intake via food (IU) | 0.37 (0.17–0.78) | 0.020 | 0.58 (0.27–1.28)† | 0.205 |
| First-degree type 1 diabetic relative | 5.15 (1.45–18.28) | 0.021 | 6.74 (1.62–28.03) | 0.031 |
| HLA-DR 3/4, DQ8 genotype | 9.79 (1.69–56.83) | 0.029 | 9.14 (1.50–55.85) | 0.054 |
| GDM | 7.78 (1.83–33.03) | 0.011 | 2.05 (0.22–19.02) | 0.528 |
| Child’s ethnicity (% non-Hispanic Caucasian) | 6.97 (0.88–55.46) | 0.088 | Not calculable‡ | NA |
| Risk factors* . | IA adjusted HR (95% CI) . | Wald χ2 P . | Persistent IA adjusted HR (95% CI) . | Wald χ2 P . |
|---|---|---|---|---|
| n | 16 | 11 | ||
| Vitamin D intake via food (IU) | 0.37 (0.17–0.78) | 0.020 | 0.58 (0.27–1.28)† | 0.205 |
| First-degree type 1 diabetic relative | 5.15 (1.45–18.28) | 0.021 | 6.74 (1.62–28.03) | 0.031 |
| HLA-DR 3/4, DQ8 genotype | 9.79 (1.69–56.83) | 0.029 | 9.14 (1.50–55.85) | 0.054 |
| GDM | 7.78 (1.83–33.03) | 0.011 | 2.05 (0.22–19.02) | 0.528 |
| Child’s ethnicity (% non-Hispanic Caucasian) | 6.97 (0.88–55.46) | 0.088 | Not calculable‡ | NA |
All variables entered into model simultaneously;
HR represents risk for a 155.6 IU SD difference in intake;
all affected were non-Hispanic Caucasian.