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Table 2—

Annual costs of statin treatment (medication, monitoring, and adverse events) per patient with diabetes and for the U.S. population with diabetes by baseline LDL cholesterol level

LDL 100–129 (mg/dl)LDL 130–149 (mg/dl)LDL 150–169 (mg/dl)LDL 170–189 (mg/dl)LDL ≥190 (mg/dl)
Population estimates (n) 3,023,000 2,243,000 2,300,000 702,000 675,000 
Atorvastatin 10 mg 20 mg 20 mg 40 mg 80 mg 
 Costs per patient/year $900 $1,300 $1,300 $1,400 $1,400 
 Total costs in population $2.66 billion $2.83 billion $2.91 billion $0.95 billion $0.92 billion 
Simvastatin 10 mg 20 mg 40 mg 80 mg  
 Costs per patient/year $1,000 $1,600 $1,600 $1,600 * 
 Total costs in population $2.91 billion $3.67 billion $3.76 billion $1.15 billion * 
Lovastatin 20 mg 40 mg 80 mg   
 Costs per patient/year $600 $1,100 $2,100 * * 
 Total costs in population $1.90 billion $2.46 billion $4.89 billion * * 
Fluvastatin 40 mg 80 mg    
 Costs per patient/year $600 $700 * * * 
 Total costs in population $1.75 billion $1.68 billion * * * 
Pravastatin 20 mg 40 mg    
 Costs per patient/year $1,000 $1,600 * * * 
 Total costs in population $3.17 billion $3.62 billion * * * 
LDL 100–129 (mg/dl)LDL 130–149 (mg/dl)LDL 150–169 (mg/dl)LDL 170–189 (mg/dl)LDL ≥190 (mg/dl)
Population estimates (n) 3,023,000 2,243,000 2,300,000 702,000 675,000 
Atorvastatin 10 mg 20 mg 20 mg 40 mg 80 mg 
 Costs per patient/year $900 $1,300 $1,300 $1,400 $1,400 
 Total costs in population $2.66 billion $2.83 billion $2.91 billion $0.95 billion $0.92 billion 
Simvastatin 10 mg 20 mg 40 mg 80 mg  
 Costs per patient/year $1,000 $1,600 $1,600 $1,600 * 
 Total costs in population $2.91 billion $3.67 billion $3.76 billion $1.15 billion * 
Lovastatin 20 mg 40 mg 80 mg   
 Costs per patient/year $600 $1,100 $2,100 * * 
 Total costs in population $1.90 billion $2.46 billion $4.89 billion * * 
Fluvastatin 40 mg 80 mg    
 Costs per patient/year $600 $700 * * * 
 Total costs in population $1.75 billion $1.68 billion * * * 
Pravastatin 20 mg 40 mg    
 Costs per patient/year $1,000 $1,600 * * * 
 Total costs in population $3.17 billion $3.62 billion * * * 
*

Goal of LDL cholesterol–lowering regimen (≤100 mg/dl) cannot be achieved. Bold entries in the table indicate the least expensive statin for each LDL cholesterol stratum.

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