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Table 3—

Annual incremental costs of statin treatment* per patient with diabetes and for the U.S. population with diabetes by baseline LDL cholesterol levels

LDL 100–129 (mg/dl)LDL 130–149 (mg/dl)LDL 150–169 (mg/dl)LDL 170–189 (mg/dl)LDL ≥190 (mg/dl)
Population estimates (n) 3,023,000 2,243,000 2,300,000 702,000 675,000 
Atorvastatin      
 Net costs per subject $780 $1,060 $1,040 $1,050 $1,020 
 Net costs for population $2.34 billion $2.38 billion $2.38 billion $0.74 billion $0.69 billion 
Simvastatin      
 Net costs per subject $850 $1,470 $1,410 $1,350  
 Net costs for population $2.58 billion $3.29 billion $3.25 billion $0.94 billion  
Lovastatin      
 Net costs per subject $530 $950 $1,920   
 Net costs for population $1.59 billion $2.12 billion $4.41 billion   
Fluvastatin      
 Net costs per subject $480 $590    
 Net costs for population $1.45 billion $1.32 billion    
Pravastatin      
 Net costs per subject $950 $1,470    
 Net costs for population $2.87 billion $3.29 billion    
LDL 100–129 (mg/dl)LDL 130–149 (mg/dl)LDL 150–169 (mg/dl)LDL 170–189 (mg/dl)LDL ≥190 (mg/dl)
Population estimates (n) 3,023,000 2,243,000 2,300,000 702,000 675,000 
Atorvastatin      
 Net costs per subject $780 $1,060 $1,040 $1,050 $1,020 
 Net costs for population $2.34 billion $2.38 billion $2.38 billion $0.74 billion $0.69 billion 
Simvastatin      
 Net costs per subject $850 $1,470 $1,410 $1,350  
 Net costs for population $2.58 billion $3.29 billion $3.25 billion $0.94 billion  
Lovastatin      
 Net costs per subject $530 $950 $1,920   
 Net costs for population $1.59 billion $2.12 billion $4.41 billion   
Fluvastatin      
 Net costs per subject $480 $590    
 Net costs for population $1.45 billion $1.32 billion    
Pravastatin      
 Net costs per subject $950 $1,470    
 Net costs for population $2.87 billion $3.29 billion    
*

Incremental costs = costs of statin treatment (medication, monitoring, and adverse events) plus costs of major coronary events with statin treatment minus cost of major coronary events without statin treatment;

Goal of LDL cholesterol–lowering regimen (≤100 mg/dl) cannot be achieved. Bold entries in the table indicate the least expensive statin for each LDL cholesterol stratum.

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