Sensitivity analysis of incremental cost of statin treatment per patient with diabetes by baseline LDL cholesterol level*
| . | LDL 100–129 (mg/dl) . | LDL 130–149 (mg/dl) . | LDL 150–169 (mg/dl) . | LDL 170–189 (mg/dl) . | LDL ≥190 (mg/dl) . |
|---|---|---|---|---|---|
| Base-case analysis | $480 | $590 | $1,040 | $1,050 | $1,020 |
| Cost of statin | |||||
| Increase by 25% | $620 | $770 | $1,350 | $1,390 | $1,360 |
| Decrease by 25% | $330 | $400 | $720 | $710 | $680 |
| Cost of coronary event | |||||
| Increase by 25% | $450 | $550 | $980 | $970 | $930 |
| Decrease by 25% | $500 | $630 | $1,090 | $1,130 | $1,100 |
| Incidence of coronary events with statin treatment | |||||
| Increase by 25% | $540 | $660 | $1,110 | $1,120 | $1,100 |
| Decrease by 25% | $410 | $510 | $960 | $970 | $930 |
| Incidence of coronary events without statin treatment | |||||
| Increase by 25% | $390 | $470 | $900 | $900 | $840 |
| Decrease by 25% | $570 | $700 | $1,170 | $1,200 | $1,190 |
| . | LDL 100–129 (mg/dl) . | LDL 130–149 (mg/dl) . | LDL 150–169 (mg/dl) . | LDL 170–189 (mg/dl) . | LDL ≥190 (mg/dl) . |
|---|---|---|---|---|---|
| Base-case analysis | $480 | $590 | $1,040 | $1,050 | $1,020 |
| Cost of statin | |||||
| Increase by 25% | $620 | $770 | $1,350 | $1,390 | $1,360 |
| Decrease by 25% | $330 | $400 | $720 | $710 | $680 |
| Cost of coronary event | |||||
| Increase by 25% | $450 | $550 | $980 | $970 | $930 |
| Decrease by 25% | $500 | $630 | $1,090 | $1,130 | $1,100 |
| Incidence of coronary events with statin treatment | |||||
| Increase by 25% | $540 | $660 | $1,110 | $1,120 | $1,100 |
| Decrease by 25% | $410 | $510 | $960 | $970 | $930 |
| Incidence of coronary events without statin treatment | |||||
| Increase by 25% | $390 | $470 | $900 | $900 | $840 |
| Decrease by 25% | $570 | $700 | $1,170 | $1,200 | $1,190 |
Base-case analysis was performed with the least-expensive statin for each LDL cholesterol stratum.