Table 4—

Sensitivity analysis of incremental cost of statin treatment per patient with diabetes by baseline LDL cholesterol level*

LDL 100–129 (mg/dl)LDL 130–149 (mg/dl)LDL 150–169 (mg/dl)LDL 170–189 (mg/dl)LDL ≥190 (mg/dl)
Base-case analysis $480$590 $1,040$1,050 $1,020 Cost of statin Increase by 25%$620 $770$1,350 $1,390$1,360
Decrease by 25% $330$400 $720$710 $680 Cost of coronary event Increase by 25%$450 $550$980 $970$930
Decrease by 25% $500$630 $1,090$1,130 $1,100 Incidence of coronary events with statin treatment Increase by 25%$540 $660$1,110 $1,120$1,100
Decrease by 25% $410$510 $960$970 $930 Incidence of coronary events without statin treatment Increase by 25%$390 $470$900 $900$840
Decrease by 25% $570$700 $1,170$1,200 $1,190 LDL 100–129 (mg/dl)LDL 130–149 (mg/dl)LDL 150–169 (mg/dl)LDL 170–189 (mg/dl)LDL ≥190 (mg/dl) Base-case analysis$480 $590$1,040 $1,050$1,020
Cost of statin
Increase by 25% $620$770 $1,350$1,390 $1,360 Decrease by 25%$330 $400$720 $710$680
Cost of coronary event
Increase by 25% $450$550 $980$970 $930 Decrease by 25%$500 $630$1,090 $1,130$1,100
Incidence of coronary events with statin treatment
Increase by 25% $540$660 $1,110$1,120 $1,100 Decrease by 25%$410 $510$960 $970$930
Incidence of coronary events without statin treatment
Increase by 25% $390$470 $900$900 $840 Decrease by 25%$570 $700$1,170 $1,200$1,190
*

Base-case analysis was performed with the least-expensive statin for each LDL cholesterol stratum.

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