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Table 4—

Sensitivity analysis of incremental cost of statin treatment per patient with diabetes by baseline LDL cholesterol level*

LDL 100–129 (mg/dl)LDL 130–149 (mg/dl)LDL 150–169 (mg/dl)LDL 170–189 (mg/dl)LDL ≥190 (mg/dl)
Base-case analysis $480 $590 $1,040 $1,050 $1,020 
Cost of statin      
 Increase by 25% $620 $770 $1,350 $1,390 $1,360 
 Decrease by 25% $330 $400 $720 $710 $680 
Cost of coronary event      
 Increase by 25% $450 $550 $980 $970 $930 
 Decrease by 25% $500 $630 $1,090 $1,130 $1,100 
Incidence of coronary events with statin treatment      
 Increase by 25% $540 $660 $1,110 $1,120 $1,100 
 Decrease by 25% $410 $510 $960 $970 $930 
Incidence of coronary events without statin treatment      
 Increase by 25% $390 $470 $900 $900 $840 
 Decrease by 25% $570 $700 $1,170 $1,200 $1,190 
LDL 100–129 (mg/dl)LDL 130–149 (mg/dl)LDL 150–169 (mg/dl)LDL 170–189 (mg/dl)LDL ≥190 (mg/dl)
Base-case analysis $480 $590 $1,040 $1,050 $1,020 
Cost of statin      
 Increase by 25% $620 $770 $1,350 $1,390 $1,360 
 Decrease by 25% $330 $400 $720 $710 $680 
Cost of coronary event      
 Increase by 25% $450 $550 $980 $970 $930 
 Decrease by 25% $500 $630 $1,090 $1,130 $1,100 
Incidence of coronary events with statin treatment      
 Increase by 25% $540 $660 $1,110 $1,120 $1,100 
 Decrease by 25% $410 $510 $960 $970 $930 
Incidence of coronary events without statin treatment      
 Increase by 25% $390 $470 $900 $900 $840 
 Decrease by 25% $570 $700 $1,170 $1,200 $1,190 
*

Base-case analysis was performed with the least-expensive statin for each LDL cholesterol stratum.

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