American Diabetes Association

Table 1—

Rates of DPN and its complications in the U.S.

Health state	Population	Estimated rate	References
		Prevalence
DPN	People with diabetes	59.40% (t1)	(13)
		49.00% (t2)
Neuropathic foot ulcer	People with diabetes	6.2% (t1)^*	(3, 17)
		6.8% (t2)^*
Not infected	People with diabetes and a foot ulcer	87.4%^†	(18)
With cellulitis		9.0%^†
With osteomyelitis		3.6%^†
		Incidence
Lower-limb amputation	People with diabetes	0.6%	(3, 19)
Toe		39.0%
Foot	Lower-limb amputations	12.0%	(20)
Leg		47.0%

Health state	Population	Estimated rate	References
		Prevalence
DPN	People with diabetes	59.40% (t1)	(13)
		49.00% (t2)
Neuropathic foot ulcer	People with diabetes	6.2% (t1)^*	(3, 17)
		6.8% (t2)^*
Not infected	People with diabetes and a foot ulcer	87.4%^†	(18)
With cellulitis		9.0%^†
With osteomyelitis		3.6%^†
		Incidence
Lower-limb amputation	People with diabetes	0.6%	(3, 19)
Toe		39.0%
Foot	Lower-limb amputations	12.0%	(20)
Leg		47.0%

Estimated prevalence rates of foot ulceration = 9.5% (type 1 diabetes) and 10.5% (type 2 diabetes); estimated proportion of foot ulcers being neuropathic = 65%.

†

Proportions of patient weeks spent in each state of ulceration. t1, type 1 diabetes; t2, type 2 diabetes.

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