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Table 1—

Rates of DPN and its complications in the U.S.

Health statePopulationEstimated rateReferences
  Prevalence  
DPN People with diabetes 59.40% (t1) (13) 
  49.00% (t2)  
Neuropathic foot ulcer People with diabetes 6.2% (t1)* (3, 17) 
  6.8% (t2)*  
Not infected People with diabetes and a foot ulcer 87.4% (18) 
With cellulitis  9.0%  
With osteomyelitis  3.6%  
  Incidence  
Lower-limb amputation People with diabetes 0.6% (3, 19) 
Toe  39.0%  
Foot Lower-limb amputations 12.0% (20) 
Leg  47.0%  
Health statePopulationEstimated rateReferences
  Prevalence  
DPN People with diabetes 59.40% (t1) (13) 
  49.00% (t2)  
Neuropathic foot ulcer People with diabetes 6.2% (t1)* (3, 17) 
  6.8% (t2)*  
Not infected People with diabetes and a foot ulcer 87.4% (18) 
With cellulitis  9.0%  
With osteomyelitis  3.6%  
  Incidence  
Lower-limb amputation People with diabetes 0.6% (3, 19) 
Toe  39.0%  
Foot Lower-limb amputations 12.0% (20) 
Leg  47.0%  
*

Estimated prevalence rates of foot ulceration = 9.5% (type 1 diabetes) and 10.5% (type 2 diabetes); estimated proportion of foot ulcers being neuropathic = 65%.

Proportions of patient weeks spent in each state of ulceration. t1, type 1 diabetes; t2, type 2 diabetes.

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