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Table 3—

Annual costs of DPN and its complications in the U.S.

Health stateType 1 diabetes
Type 2 diabetes
All diabetes
PatientsAnnual cost ($ millions)PatientsAnnual cost ($ millions)PatientsAnnual cost ($ millions)
Diabetes (type)* 832,500 — 10,267,500 — 11,100,000 — 
DPN* 494,505 $21 5,027,995 $216 5,522,500 $237 
Foot ulcer       
Not infected* 44,917 $418 612,290 $5,698 657,207 $6,116 
With cellulitis* 4,632 $114 63,144 $1,552 67,776 $1,666 
With osteomyelitis* 1,858 $85 25,323 $1,154 27,181 $1,239 
Amputation       
 Toe 1,266 $29 15,617 $355 16,883 $383 
 Foot 390 $17 4,805 $205 5,195 $222 
 Leg 1,526 $78 18,820 $965 20,346 $1,043 
 Total annual cost — $761 — $10,145 — $10,907 
Health stateType 1 diabetes
Type 2 diabetes
All diabetes
PatientsAnnual cost ($ millions)PatientsAnnual cost ($ millions)PatientsAnnual cost ($ millions)
Diabetes (type)* 832,500 — 10,267,500 — 11,100,000 — 
DPN* 494,505 $21 5,027,995 $216 5,522,500 $237 
Foot ulcer       
Not infected* 44,917 $418 612,290 $5,698 657,207 $6,116 
With cellulitis* 4,632 $114 63,144 $1,552 67,776 $1,666 
With osteomyelitis* 1,858 $85 25,323 $1,154 27,181 $1,239 
Amputation       
 Toe 1,266 $29 15,617 $355 16,883 $383 
 Foot 390 $17 4,805 $205 5,195 $222 
 Leg 1,526 $78 18,820 $965 20,346 $1,043 
 Total annual cost — $761 — $10,145 — $10,907 
*

Number of patients at a given point in time;

number of new cases per year.

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