American Diabetes Association

Table 2—

Stepwise multiple regression to quantify the independent contribution of adiponectin, viseral adipose tissue, and leptin to insulin sensitivity

Dependent variable	Step	Independent variable	P	R²
Insulin sensitivity	1	Tanner stage	<0.001
		Sex	0.320
		Race	0.233	0.21

	2	Tanner stage	<0.001
		Sex	0.045
		Race	0.744
		Adiponectin	<0.001	0.48

	3	Tanner stage	<0.001
		Sex	0.037
		Race	0.255
		Adiponectin	<0.001
		VAT	<0.001	0.60

	4	Tanner stage	<0.001
		Sex	0.896
		Race	0.686
		Adiponectin	<0.001
		VAT	0.125
		Leptin	<0.001	0.64

Dependent variable	Step	Independent variable	P	R²
Insulin sensitivity	1	Tanner stage	<0.001
		Sex	0.320
		Race	0.233	0.21

	2	Tanner stage	<0.001
		Sex	0.045
		Race	0.744
		Adiponectin	<0.001	0.48

	3	Tanner stage	<0.001
		Sex	0.037
		Race	0.255
		Adiponectin	<0.001
		VAT	<0.001	0.60

	4	Tanner stage	<0.001
		Sex	0.896
		Race	0.686
		Adiponectin	<0.001
		VAT	0.125
		Leptin	<0.001	0.64

Insulin sensitivity, adiponectin, viseral adipose tissue, and leptin were log transformed to normalize their distribution. VAT, viseral adipose tissue.

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