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Table 1—

Demographic, anthropometric, cardiovascular, humoral, and clinical parameters of the study patients

Type 1 diabetes
Type 2 diabetes
P value
Male subjectsFemale subjectsAllMale subjectsFemale subjectsAll
n 317 321 638 3,911 3,948 7,859  
Age (years) 47 ± 17 50 ± 18 48 ± 17 64 ± 11 66 ± 11 65 ± 11 <0.0001 
Duration of disease (years) 15 ± 11 17 ± 12 16 ± 11 10 ± 8.0 11 ± 8.0 10 ± 8.0 <0.0001 
BMI (kg/m224.8 ± 3.6 25.0 ± 5.5 24.9 ± 4.6 28.4 ± 4.3 30.0 ± 5.6 29.2 ± 5.1 <0.0001 
Waist (cm) 89 ± 13 84 ± 16 87 ± 15 99 ± 13 98 ± 15 98 ± 14 <0.0001 
Fasting plasma glucose (mmol/l) 10 ± 4.3 9.6 ± 3.7 9.8 ± 4.0 8.8 ± 2.8 9.0 ± 2.8 8.9 ± 2.8 <0.0001 
A1C (%) 7.9 ± 1.7 8.0 ± 1.5 8.0 ± 1.6 7.5 ± 1.9 7.7 ± 1.5 7.6 ± 1.7 <0.0001 
Creatinine (μmol/l) 87 ± 53 88 ± 53 88 ± 53 88 ± 44 89 ± 52 88 ± 44 0.287 
Systolic blood pressure (mmHg) 132 ± 18 130 ± 19 131 ± 19 141 ± 18 143 ± 18 142 ± 18 <0.0001 
Diastolic blood pressure (mmHg) 79 ± 10 78 ± 9.9 79 ± 10 82 ± 9.7 82 ± 10 82 ± 9.8 <0.0001 
LDL cholesterol (mmol/l) 2.9 ± 0.9 3.0 ± 1.0 2.9 ± 0.9 3.2 ± 0.9 3.3 ± 1.0 3.2 ± 0.9 <0.0001 
HDL cholesterol (mmol/l) 1.3 ± 0.3 1.4 ± 0.4 1.4 ± 0.4 1.2 ± 0.3 1.3 ± 0.3 1.2 ± 0.3 <0.0001 
Triglycerides (mmol/l) 1.5 ± 0.8 1.4 ± 1.0 1.4 ± 0.9 1.9 ± 1.0 1.8 ± 0.9 1.9 ± 1.0 <0.0001 
AHA/NHLBI metabolic syndrome (%) 24.5 43.2 33.7 58.8 80.8 69.5 <0.0001 
IDF metabolic syndrome (%) 34.1 47.6 40.8 69.5 85.6 77.6 <0.0001 
Type 1 diabetes
Type 2 diabetes
P value
Male subjectsFemale subjectsAllMale subjectsFemale subjectsAll
n 317 321 638 3,911 3,948 7,859  
Age (years) 47 ± 17 50 ± 18 48 ± 17 64 ± 11 66 ± 11 65 ± 11 <0.0001 
Duration of disease (years) 15 ± 11 17 ± 12 16 ± 11 10 ± 8.0 11 ± 8.0 10 ± 8.0 <0.0001 
BMI (kg/m224.8 ± 3.6 25.0 ± 5.5 24.9 ± 4.6 28.4 ± 4.3 30.0 ± 5.6 29.2 ± 5.1 <0.0001 
Waist (cm) 89 ± 13 84 ± 16 87 ± 15 99 ± 13 98 ± 15 98 ± 14 <0.0001 
Fasting plasma glucose (mmol/l) 10 ± 4.3 9.6 ± 3.7 9.8 ± 4.0 8.8 ± 2.8 9.0 ± 2.8 8.9 ± 2.8 <0.0001 
A1C (%) 7.9 ± 1.7 8.0 ± 1.5 8.0 ± 1.6 7.5 ± 1.9 7.7 ± 1.5 7.6 ± 1.7 <0.0001 
Creatinine (μmol/l) 87 ± 53 88 ± 53 88 ± 53 88 ± 44 89 ± 52 88 ± 44 0.287 
Systolic blood pressure (mmHg) 132 ± 18 130 ± 19 131 ± 19 141 ± 18 143 ± 18 142 ± 18 <0.0001 
Diastolic blood pressure (mmHg) 79 ± 10 78 ± 9.9 79 ± 10 82 ± 9.7 82 ± 10 82 ± 9.8 <0.0001 
LDL cholesterol (mmol/l) 2.9 ± 0.9 3.0 ± 1.0 2.9 ± 0.9 3.2 ± 0.9 3.3 ± 1.0 3.2 ± 0.9 <0.0001 
HDL cholesterol (mmol/l) 1.3 ± 0.3 1.4 ± 0.4 1.4 ± 0.4 1.2 ± 0.3 1.3 ± 0.3 1.2 ± 0.3 <0.0001 
Triglycerides (mmol/l) 1.5 ± 0.8 1.4 ± 1.0 1.4 ± 0.9 1.9 ± 1.0 1.8 ± 0.9 1.9 ± 1.0 <0.0001 
AHA/NHLBI metabolic syndrome (%) 24.5 43.2 33.7 58.8 80.8 69.5 <0.0001 
IDF metabolic syndrome (%) 34.1 47.6 40.8 69.5 85.6 77.6 <0.0001 

Continuous variables are means ± SD. P values refer to the comparison between type 1 and type 2 diabetic patients. Prevalence of IDF-defined metabolic syndrome was significantly higher (P < 0.01) than prevalence of AHA/NHLBI-defined metabolic syndrome in both types of diabetes.

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