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Table 2—

HR (95% CI) for mortality associated with the number of metabolic syndrome components in 1,141 men and 977 women of the Rancho Bernardo Study

OutcomesNumber of componentsnDeaths (women/men)HR (95%CI)*
Total populationWomenMen
CHD 405 29 (12/17) 
 875 127 (58/69) 1.19 (0.79–1.79) 1.13 (0.60–2.12) 1.26 (0.74–2.15) 
 501 72 (29/43) 1.17 (0.75–1.80) 1.25 (0.63–2.46) 1.11 (0.63–1.95) 
 213 33 (17/16) 1.55 (0.93–2.57) 1.83 (0.86–3.91) 1.35 (0.68–2.69) 
 98 21 (13/8) 2.00 (1.13–3.64) 2.21 (0.97–5.02) 1.96 (0.84–4.59) 
 26 11 (4/7) 4.12 (2.04–8.32) 3.18 (1.00–10.1) 5.08 (2.09–12.4) 
    Ptrend = 0.0002 Ptrend = 0.004 Ptrend = 0.02 
CHD <3 1,781 228 (99/129) 
 ≥3 337 65 (34/31) 1.63 (1.23–2.16) 1.80 (1.18–2.73) 1.54 (1.04–2.29) 
Stroke <3 1,781 110 (55/55) 
 ≥3 337 22 (13/9) 1.28 (0.80–2.05) 1.84 (0.98–3.47) 1.04 (0.51–2.12) 
CVD <3 1,781 519 (245/274) 
 ≥3 337 128 (74/54) 1.50 (1.23–1.83) 1.18 (1.38–2.39) 1.28 (0.95–1.71) 
All causes <3 1,781 1,048 (514/534) 
 ≥3 337 241 (118/123) 1.43 (1.24–1.65) 1.46 (1.19–1.80) 1.44 (1.18–1.76) 
OutcomesNumber of componentsnDeaths (women/men)HR (95%CI)*
Total populationWomenMen
CHD 405 29 (12/17) 
 875 127 (58/69) 1.19 (0.79–1.79) 1.13 (0.60–2.12) 1.26 (0.74–2.15) 
 501 72 (29/43) 1.17 (0.75–1.80) 1.25 (0.63–2.46) 1.11 (0.63–1.95) 
 213 33 (17/16) 1.55 (0.93–2.57) 1.83 (0.86–3.91) 1.35 (0.68–2.69) 
 98 21 (13/8) 2.00 (1.13–3.64) 2.21 (0.97–5.02) 1.96 (0.84–4.59) 
 26 11 (4/7) 4.12 (2.04–8.32) 3.18 (1.00–10.1) 5.08 (2.09–12.4) 
    Ptrend = 0.0002 Ptrend = 0.004 Ptrend = 0.02 
CHD <3 1,781 228 (99/129) 
 ≥3 337 65 (34/31) 1.63 (1.23–2.16) 1.80 (1.18–2.73) 1.54 (1.04–2.29) 
Stroke <3 1,781 110 (55/55) 
 ≥3 337 22 (13/9) 1.28 (0.80–2.05) 1.84 (0.98–3.47) 1.04 (0.51–2.12) 
CVD <3 1,781 519 (245/274) 
 ≥3 337 128 (74/54) 1.50 (1.23–1.83) 1.18 (1.38–2.39) 1.28 (0.95–1.71) 
All causes <3 1,781 1,048 (514/534) 
 ≥3 337 241 (118/123) 1.43 (1.24–1.65) 1.46 (1.19–1.80) 1.44 (1.18–1.76) 
*

Adjusted for age and sex, as appropriate, smoking, and LDL cholesterol; sex interaction P values = 0.6, 0.6, 0.2, and 0.9 for mortality from CHD, stroke, CVD, and all causes, respectively.

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